Management of Subjects with Type 2 Diabetes Hospitalized in Internal Medicine Units: A Cluster-Randomized, Multicenter Study Before & After an Educational Program

Introduction: Few data are available relatively to the adherence to treatment guidelines in individuals with type 2 diabetes mellitus (T2DM) admitted to Internal Medicine Wards (IMW) while no information is available relatively to the possible efficacy of an educational intervention aimed at implementing adherence in this setting. Methods: To explore guidelines adherence and the relative impact on glycemic control in subjects with T2DM hospitalized in IMW before and after an educational intervention, we conducted a 3-phase, cluster-randomized, multicenter study. During phase 1, we retrospectively collected data from patients with T2DM hospitalized for any cause in IMW for ≥ 5 days. In phase 2, an educational training, based on the method of the educational outreach visits (EOV), was developed in 36 out of the 54 centers involved. In phase 3, done 6 months after the training, we replicated the collection of data performed in phase 1. Results: Overall, we analyzed data from 1909 and 1662 individuals with T2DM during the phase 1 and phase 3 of the study, respectively. No changes were observed in the difference between mean fasting glycemia levels at discharge vs at admission at Phase 3 comparing EOV vs NO EOV groups. A statistically significant increase in adherence to guidelines was observed from Phase 1 to Phase 3 and a trend of higher adherence was detected when comparing the EOV and the no EOV groups. A structured educational intervention improves adherence to guidelines for managing T2DM in individuals admitted to IMW but has no effect on short-term glycemic control.