Rare Presentation of Cervical Choriocarcinoma with Metastasis: A Case Report

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Abstract

Introduction: Choriocarcinoma of the cervix is an extremely rare sporadic disease with an incidence of 0.76 to 4%. This malignant form of gestational trophoblastic disease typically originates in the uterus but can occasionally arise in the vagina, fallopian tubes, vulva, cervix, or pelvic region. Case Presentation: Our patient presented with heavy menstrual bleeding and elevated B-HCG levels. She underwent total hysterectomy with bilateral salpingo-oophorectomy (TAH + BSO). Histopathological diagnosis confirmed choriocarcinoma and a post-treatment CT scan revealed lung metastasis. Treatment usually involves combination chemotherapy, which is highly effective, with cure rates reaching 100% in low-risk patients and 80–90% in high-risk patients. Conclusion: This report highlights the importance of a meticulous, multidisciplinary approach in managing patients who present with choriocarcinoma at unusual sites like cervix that can easily be missed and misdiagnosed.

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