Blood Flow Simulation in Bifurcating Arteries, a Multiscale Approach After Fenestrated and Branched Endovascular Aneurysm Repair

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Abstract

Pathophysiological conditions in arteries, such as stenosis or aneurysms, have a great impact on blood flow dynamics enforcing the numerical study of such pathologies. Computational fluid dynamics (CFD) could provide the means for the calculation and interpretation of pressure and velocity fields, wall stresses and important biomedical factors in such pathologies. Additionally, most of these pathological conditions are connected with geometric vessel changes. In this study, the numerical solution of the 2D flow in a branching artery and a multiscale model of 3D flow are presented utilizing CFD. In the 3D case, a multiscale approach (3D and 0D-1D) is pursued, in which a dynamically altered velocity parabolic profile is applied at the inlet of the geometry. The obtained waveforms are derived from a 0D-1D mathematical model of the entire arterial tree. The geometries of interest are patient-specific 3D reconstructed abdominal aortic aneurysms after fenestrated (FEVAR) and branched endovascular aneurysm repair (BEVAR). Critical hemodynamic parameters such as velocity, wall shear stress, time averaged wall shear stress and local normalized helicity are presented, evaluated and compared.

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