Liposomal Nanocarriers From Concept to Clinical Applications

Liposomal drug delivery systems have been used as an innovation tool in nanomedicine to show improved drug stability, release control, and targeted therapy. The review provided in this chapter reviews the evolutionary history of liposomes, constitutional structure, and classification. Mechanistic attributes of drug release, stealth liposomes, and functionalized carriers reflect innovations that deliver the best in therapeutic efficacy. Their use in cancer therapy, crossing the blood-brain barrier, infection, and gene therapy are a few examples of their utility in contemporary medicine. Liposomes are more biocompatible and provide controlled drug release compared to polymeric nanoparticles but are difficult for stability and large-scale production. Scanning and regulation are also obstacles to commercialization. But there is hope in the following positive trends: AI-aided liposomal design, hybrid nanocarriers, and theranostic use, which shall be the next-generation drug delivery systems. This review presents an overall impression of the development, challenge, and future trend of liposomes, which is engaged in the construction of precision medicine.