ClipKIT in the Browser: Fast Online Trimming of Multiple Sequence Alignments for Phylogenetics

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Abstract

Multiple sequence alignment trimming can help improve phylogenetic signal and reduce computational load. ClipKIT trims multiple sequence alignments by retaining phylogenetically informative sites and removing all others. Here, we present a web browser application for ClipKIT, which supports DNA, protein, and codon data types in FASTA format. The web browser application can process one or many multiple sequence alignment files, which users can subsequently download. Users can also view the trimmed multiple sequence alignment using a web-based multiple sequence alignment viewer. ClipKIT is available at https://clipkit.genomelybio.com, is free and open to all users, and there is no login requirement. ClipKIT in the browser aims to broaden the accessibility of web-based tools for phylogenetics research.

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