Impact of Praziquantel Mass Drug Administration after Several Rounds on Schistosomiasis Among School-Aged Children in Abuja, Nigeria

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Abstract

Introduction: One of the global strategies for elimination of schistosomiasis is by mass treatment of school-aged children with a single oral dose of praziquantel (40mg/kg) without a prior individual diagnosis, with a target of >75% treatment coverage. This study was conducted to determine the endemicity of schistosomiasis among school-aged children and adults in Abuja, Nigeria. Methods: A total of 1,370 participants were recruited which consisted of 667 (48.67%) males and 703 (51.31%) females. Urine and stool specimens were collected from each participant and analyzed using standard procedures. Results: The overall prevalence of schistosomiasis was 27.5% in this study with Abuja Municipal having the highest prevalence of 49% while the least (6.1%) was reported in Bwari LCA. The prevalence of schistosomiasis significantly differs (P

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