The HSP110/HSP70 disaggregation system generates spreading‐competent toxic α‐synuclein species

  1. Jessica Tittelmeier
  2. Carl Alexander Sandhof
  3. Heidrun Maja Ries
  4. Silke Druffel‐Augustin
  5. Axel Mogk
  6. Bernd Bukau
  7. Carmen Nussbaum‐Krammer

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Abstract

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  1. Version published to 10.15252/embj.2019103954
  2. preLights

    Excerpt

    Two sides of the same coin: Hsp110 activity protects against amorphous protein aggregation, but promotes amyloid aggregation and toxicity in C. elegans models

  3. Version published to 10.1101/795435 on bioRxiv