Global, regional, and national estimates of target population sizes for covid-19 vaccination: descriptive study

Article activity feed

1. 

   ScreenIT

   Mar 1, 2021

   SciScore for 10.1101/2020.09.29.20200469: (What is this?)

   Please note, not all rigor criteria are appropriate for all manuscripts.

   Table 1: Rigor

   Institutional Review Board Statement	not detected.
   Randomization	not detected.
   Blinding	not detected.
   Power Analysis	not detected.
   Sex as a biological variable	Second, to reduce severe COVID-19 disease (i.e., hospitalizations, critical care admissions, and deaths), people with underlying conditions [i.e., cardiovascular disease, chronic kidney disease, chronic respiratory disease, chronic liver disease, diabetes, cancer with direct immunosuppression, cancer without direct immunosuppression but with possible immunosuppression caused by treatment, HIV/AIDS, tuberculosis (excluding latent infections), chronic neurological disorders and sickle cell disorders] (14), those older than 60 years of age without …

   SciScore for 10.1101/2020.09.29.20200469: (What is this?)

   Please note, not all rigor criteria are appropriate for all manuscripts.

   Table 1: Rigor

   Institutional Review Board Statement	not detected.
   Randomization	not detected.
   Blinding	not detected.
   Power Analysis	not detected.
   Sex as a biological variable	Second, to reduce severe COVID-19 disease (i.e., hospitalizations, critical care admissions, and deaths), people with underlying conditions [i.e., cardiovascular disease, chronic kidney disease, chronic respiratory disease, chronic liver disease, diabetes, cancer with direct immunosuppression, cancer without direct immunosuppression but with possible immunosuppression caused by treatment, HIV/AIDS, tuberculosis (excluding latent infections), chronic neurological disorders and sickle cell disorders] (14), those older than 60 years of age without any underlying conditions, as well as pregnant women should be included as a candidate priority groups.

   Table 2: Resources

   Software and Algorithms
   Sentences	Resources
   S1 for data sources), including the 1) United Nations (UN) mid-year population estimates for 2020 for 194 WHO member states (and countries/territories); 2) country-specific sizes of the military population from the World Bank Group or searching Baidu, Bing, and Google search engines using the search terms “military size” and World Health Organization country names; 3) the density of physicians, nurses and midwiferies by country from the World Bank and the World Health Organization; 4) the number of people working in the electricity, gas, water, steam and air conditioning sectors, food, accommodation, domestic transportation and storage industries, using census data on economically active population in 152 countries; 5) the number of individuals at increased risk of severe COVID-19 by age and country from previous report by Clark A, et al. (14).	Google suggested: (Google, RRID:SCR_017097)

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   Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).

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   Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:

   Given these limitations, between-country variations in vaccine acceptance and delivery need to be considered when tailoring COVID-19 vaccine allocation and distribution to each locale. We estimated that approximately 15.6 billion doses of a COVID-19 vaccine will be requested by 194 WHO Member States for a universal COVID-19 vaccination program, given a two-dose regimen. Assuming all of the vaccine manufacturers with existing candidates can offer vaccines concurrently, the global production capacity of COVID-19 vaccine is estimated at 3.5 billion doses annually (7). Not enough vaccine will be available at the beginning of a COVID-19 vaccination program, even in an optimistic scenario. To achieve herd immunity by protecting at least 60-80% of individuals (4.7 to 6.2 billion), it will take about 17 to 22 months to produce enough COVID-19 vaccines. Vaccine supply and delivery services will constrain the roll-out of COVID-19 vaccination programs as well. In this context, the same barriers would apply to all target groups, but vaccination of targeted occupational or high-risk groups will likely be more feasible than the general public without any underlying conditions. This together comprise an estimated 2.51 billion people in 194 WHO Member States. Within- and between-region disparities in the distribution of each target population highlight different demands for COVID-19 vaccine. These disparities will result in different durations of vaccination program, due to global limitation...

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   Results from TrialIdentifier: No clinical trial numbers were referenced.

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   Results from Barzooka: We did not find any issues relating to the usage of bar graphs.

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   Results from JetFighter: We did not find any issues relating to colormaps.

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   Results from rtransparent:

   • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
   • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
   • No protocol registration statement was detected.

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2. Version published to 10.1136/bmj.m4704

   Dec 15, 2020
3. 

   Version published to 10.1101/2020.09.29.20200469 on medRxiv

   Sep 30, 2020