Single-cell analysis of human B cell maturation predicts how antibody class switching shapes selection dynamics

  1. Hamish W. King
  2. Nara Orban
  3. John C. Riches
  4. Andrew J. Clear
  5. Gary Warnes
  6. Sarah A. Teichmann
  7. Louisa K. James

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Abstract

Integrated single-cell transcriptomic and BCR analyses reveal how antibody class switching influences human B cell fate and function.

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  1. Version published to 10.1126/sciimmunol.abe6291
  3. Version published to 10.1101/2020.04.28.054775 on bioRxiv