Vaccine nationalism and the dynamics and control of SARS-CoV-2
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Abstract
A triumph that has emerged from the catastrophe of the severe acute respiratory syndrome coronavirus 2 pandemic has been the rapid development of several potent vaccines. However, 18 months into the pandemic and more than 6 months after vaccine approval, wealthy countries remain the major beneficiaries. Wagner et al . model the consequences of vaccine stockpiling in affluent countries on disease rates in lower- and middle-income countries and the consequences for the eruption of new variants that could jeopardize the early success of vaccines. For countries that can readily access vaccines, it would be better to share vaccines equitably to lower disease burdens in countries with less access, reduce the cost of having to be constantly vigilant for case imports, and minimize virus evolution. —CA
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SciScore for 10.1101/2021.06.02.21258229: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics not detected. Sex as a biological variable not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:Caveats: A full list of caveats and future directions is presented in Supplementary Materials; we briefly summarize them below. First, building on prior work and in order to focus on qualitative features, we ignore heterogeneities within countries, such as …
SciScore for 10.1101/2021.06.02.21258229: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics not detected. Sex as a biological variable not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:Caveats: A full list of caveats and future directions is presented in Supplementary Materials; we briefly summarize them below. First, building on prior work and in order to focus on qualitative features, we ignore heterogeneities within countries, such as due to age (30) or superspreading (31). Similarly, we have assumed simple scenarios for nonpharmaceutical interventions as in (6). More granular, well-parameterized epidemiological models with these complexities would lead to more accurate quantitative predictions. Furthermore, additional booster doses may be administered that could alter population-level immune landscapes, and including these in future models will be important for qualitative and quantitative predictions. Additionally, we omit vaccine hesitancy (32), though simple extensions of our previous models with hesitancy (5, 6) could examine the resulting interplay with vaccine nationalism. Furthermore, we have assumed the simplest evolutionary models, both for determining potential viral adaptation rates as well as for simulating potential increases in transmission rates. As more data become available, these should be refined (33–36), with possible directions including extending the model to explicitly track the transmission of different strains, and accounting for potential reductions in the strength of vaccinal immunity (i.e. the parameters , ϵ1, and ϵ2) due to the emergence of novel variants (37). Lastly, we assume that the seasonal transmission rates are simil...
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
Results from scite Reference Check: We found no unreliable references.
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