Cell patterning by secretion-induced plasma membrane flows

  1. Veneta Gerganova
  2. Iker Lamas
  3. David M. Rutkowski
  4. Aleksandar Vještica
  5. Daniela Gallo Castro
  6. Vincent Vincenzetti
  7. Dimitrios Vavylonis
  8. Sophie G. Martin

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Abstract

Exocytosis causes bulk membrane flows that drag associated proteins and form a negative feedback restricting the exocytic site.

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  1. Version published to 10.1126/sciadv.abg6718
  2. preLights

    Excerpt

    Rga4, a Cdc42 GAP, goes with the flow: constraining Cdc42 activity to the growing tips of fission yeast depends on membrane flows, and the slow diffusion and low detachment rate of Rga4 in the membrane.

  3. Version published to 10.1101/2020.12.18.423457 on bioRxiv