Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis

  1. Taylor S. Adams
  2. Jonas C. Schupp
  3. Sergio Poli
  4. Ehab A. Ayaub
  5. Nir Neumark
  6. Farida Ahangari
  7. Sarah G. Chu
  8. Benjamin A. Raby
  9. Giuseppe DeIuliis
  10. Michael Januszyk
  11. Qiaonan Duan
  12. Heather A. Arnett
  13. Asim Siddiqui
  14. George R. Washko
  15. Robert Homer
  16. Xiting Yan
  17. Ivan O. Rosas
  18. Naftali Kaminski

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Abstract

Human lung single-cell atlas reveals the complexity and diversity of aberrant cellular populations in pulmonary fibrosis.

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  1. Version published to 10.1126/sciadv.aba1983
  2. Version published to 10.1101/759902v3 on bioRxiv
  3. preLights

    Excerpt

    The application of single cell RNA sequencing (scRNAseq) approaches in the context of idiopathic pulmonary fibrosis (IPF) highlights dramatic remodelling of epithelial, stromal and vascular transcriptomes.

  4. Version published to 10.1101/759902v2 on bioRxiv
  5. Version published to 10.1101/759902v1 on bioRxiv