First Sin Nombre virus (Orthohantavirus sinnombreense) genome sequences from the Northwestern United States

  1. Grant Rickard
  2. Ricardo Rivero
  3. A Catherine Grady
  4. Jennifer A Horton
  5. Cody Lauritsen
  6. Stephen Fawcett
  7. Samuel Goodfellow
  8. Hanna N Oltean
  9. M. Pilar Fernandez
  10. Stephanie N. Seifert
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Abstract

We report the first Sin Nombre virus (SNV) genome sequences from the Northwestern United States and the first SNV sequences recovered from voles. Analysis of samples collected from 189 individual rodents revealed high SNV prevalence in the region and evidence of viral reassortment, highlighting ongoing viral diversification in rodents.

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  1. Version published to 10.1101/2025.09.10.675434 on bioRxiv