Association of race, ethnicity, and area deprivation with the prevalence of atrial fibrillation in a large US population
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Objective
To examine the association of atrial fibrillation (AF) prevalence with neighborhood deprivation in a large, national U.S. population across racial and ethnic groups and its association.
Methods
We analyzed data from Epic Cosmos, comprising over 56 million adults with demographic and area deprivation index data in 2024. AF prevalence was defined using ICD-10 codes.
Results
Overall AF prevalence was 3.7%, higher in men and older adults. Prevalence varied by race/ethnicity, highest in White and American Indian/Alaska Native individuals, and lowest in Asian and Hispanic individuals. AF prevalence increased with higher deprivation across most groups.
Conclusion
Area-level socioeconomic deprivation was independently associated with higher AF prevalence across all racial and ethnic groups. These findings underscore the importance of addressing structural determinants of health to reduce the burden of AF in diverse communities.
