The pulvinar regulates plasticity in human visual cortex

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Abstract

In normally sighted human adults, two-hours of monocular deprivation is sufficient to transiently alter ocular dominance. Here we show that this is associated with a reduction of functional connectivity between the pulvinar and early visual cortex, selective for the pulvinar-to-V1 directionality. Our results support a revised model of adult V1 plasticity, where short-term reorganization is gated by modulatory signals relayed by the pulvinar.

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