FlashFold: a standalone command-line tool for accelerated protein structure prediction

FlashFold is a fast, user-friendly tool for predicting protein structures and complexes. It can be installed locally on Linux or Mac operating systems, alleviating the computational needs, and eliminating reliance on third-party servers. FlashFold relies on a highly compact and adaptable built-in database to speed up the homology searching. Overall structure predictions are up to 3-fold faster than AlphaFold3 with sacrificing little or no accuracy. FlashFold is available at https://github.com/chayan7/flashfold .