Impact of COVID-19 non-pharmaceutical interventions on pneumococcal carriage prevalence and density in Vietnam

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1. 

   ScreenIT

   May 10, 2022

   SciScore for 10.1101/2022.05.05.22274646: (What is this?)

   Please note, not all rigor criteria are appropriate for all manuscripts.

   Table 1: Rigor

   Ethics	not detected.
   Sex as a biological variable	not detected.
   Randomization	not detected.
   Blinding	not detected.
   Power Analysis	not detected.

   Table 2: Resources

   Software and Algorithms
   Sentences	Resources
   Statistical analyses were conducted using Stata v16.0	Stata suggested: (Stata, RRID:SCR_012763)
   (StataCorp LLC).	StataCorp suggested: (Stata, RRID:SCR_012763)

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   Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).

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   Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:

   One limitation is that other temporal changes may have occurred during the study that …

   SciScore for 10.1101/2022.05.05.22274646: (What is this?)

   Please note, not all rigor criteria are appropriate for all manuscripts.

   Table 1: Rigor

   Ethics	not detected.
   Sex as a biological variable	not detected.
   Randomization	not detected.
   Blinding	not detected.
   Power Analysis	not detected.

   Table 2: Resources

   Software and Algorithms
   Sentences	Resources
   Statistical analyses were conducted using Stata v16.0	Stata suggested: (Stata, RRID:SCR_012763)
   (StataCorp LLC).	StataCorp suggested: (Stata, RRID:SCR_012763)

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   Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).

   ---

   Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:

   One limitation is that other temporal changes may have occurred during the study that were not accounted for. The implementation of NPIs has been associated with suppression of circulating respiratory viruses.[4] Such viruses are known to increase pneumococcal carriage density,[6,7] which is a risk factor for disease.[7,10] The decline we observed in pneumococcal density associated with NPI implementation therefore provides a plausible mechanism for the reductions in IPD that have been observed elsewhere in the absence of a substantive reduction in carriage prevalence. Further research examining the links between pneumococcal carriage, density, and respiratory viruses is needed to fully elucidate the impact NPIs have on IPD.

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   Results from TrialIdentifier: We found the following clinical trial numbers in your paper:
   

   Identifier	Status	Title
   NCT03098628	Active, not recruiting	Trial of Simplified Pneumococcal Vaccination in Vietnam II

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   Results from Barzooka: We did not find any issues relating to the usage of bar graphs.

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   Results from JetFighter: We did not find any issues relating to colormaps.

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   Results from rtransparent:

   • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
   • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
   • No protocol registration statement was detected.

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   Results from scite Reference Check: We found no unreliable references.

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   Read the original source
2. 

   Version published to 10.1101/2022.05.05.22274646v1 on medRxiv

   May 7, 2022