Increase in preterm stillbirths in association with reduction in iatrogenic preterm births during COVID-19 lockdown in Australia: a multicenter cohort study
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SciScore for 10.1101/2021.10.04.21264500: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics IRB: Ethical approval: This study was given ethical approval from the Human Research Ethics Committees of Austin Health (Ref. Sex as a biological variable An estimated 44,000 women give birth in the participating hospitals each year, representing approximately three quarters of all hospital births in Melbourne. Randomization not detected. Blinding not detected. Power Analysis Primary outcomes: Secondary outcomes: Statistical analysis: No sample size calculation was performed as this was a cohort defined by lockdown duration. Table 2: Resources
Software and Algorithms Sentences Resources College Station, TX: StataCorp LLC), and two-sided p-values below 0.05 were considered statistically significant. Stata…SciScore for 10.1101/2021.10.04.21264500: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics IRB: Ethical approval: This study was given ethical approval from the Human Research Ethics Committees of Austin Health (Ref. Sex as a biological variable An estimated 44,000 women give birth in the participating hospitals each year, representing approximately three quarters of all hospital births in Melbourne. Randomization not detected. Blinding not detected. Power Analysis Primary outcomes: Secondary outcomes: Statistical analysis: No sample size calculation was performed as this was a cohort defined by lockdown duration. Table 2: Resources
Software and Algorithms Sentences Resources College Station, TX: StataCorp LLC), and two-sided p-values below 0.05 were considered statistically significant. StataCorpsuggested: (Stata, RRID:SCR_012763)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:Our present Melbourne-wide dataset was sufficiently powered to examine stillbirth as a primary outcome, overcoming many of the limitations of single institution studies. The forest plots demonstrated consistent trends across each hospital and service capability levels, demonstrating that the changes in primary outcomes are most plausibly due to the effect of lockdown rather than any other variable. An incidental finding was a marked decline in weekly pregnancies at the onset of the lockdown in March and April 2020, followed by a rebound in May and June 2020. It appears that many women who might have otherwise planned to conceive when the national state of emergency was announced on 16 March 2020 delayed conception until June, when the first lockdown restrictions eased. This shift in conceptions would also explain the small increase in median maternal age of one month in the lockdown cohort. This phenomenon of a steep decline in births followed by a “baby boom” is a well-established pattern associated with pandemics.29 Strengths: Melbourne is a unique case study for the impact of pandemic restrictions on pregnancy outcomes due to the stringency and length of lockdown and the lack of significant health system strain or COVID-19 maternity caseload. Our adverse results can therefore be solely attributed to indirect effects of the pandemic. Our report has the strengths of a large sample size and complete ascertainment of all public hospital births. In any study examining preterm b...
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
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- No protocol registration statement was detected.
Results from scite Reference Check: We found no unreliable references.
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