The short flagella 1 (SHF1) gene in Chlamydomonas encodes a Crescerin TOG-domain protein required for late stages of flagellar growth
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Abstract
The SHF1 gene of Chlamydomonas encodes a Crescerin family TOG-domain protein required for flagella to attain full length. Mutants in SHF1 grow at normal speed but then stop going when flagella reach half length. A combination of measurements and modeling suggest that the protein is functioning to promote tubulin transport during flagellar assembly.
