The King’s College London Coronavirus Health and Experiences of Colleagues at King’s Study: SARS-CoV-2 antibody response in an occupational sample
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Abstract
We report test results for SARS-CoV-2 antibodies in an occupational group of postgraduate research students and current members of staff at King’s College London. Between June and July 2020, antibody testing kits were sent to n = 2296 participants; n = 2004 (86.3%) responded, of whom n = 1882 (93.9%) returned valid test results. Of those that returned valid results, n = 124 (6.6%) tested positive for SARS-CoV-2 antibodies, with initial comparisons showing variation by age group and clinical exposure.
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SciScore for 10.1101/2020.09.10.20191841: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Antibodies Sentences Resources A Rapid Immunoglobulin Test Cassette was used to detect the presence of IgM and IgG antibodies to the ‘spike’ protein, thereby providing evidence for previous infection with SARS-CoV-2. SureScreen Diagnostics COVID-19 IgG/IgM Rapid Test Cassettes, the necessary equipment and detailed instructions were sent to participants’ home address. IgGsuggested: NoneSoftware and Algorithms Sentences Resources Statistical analysis: Statistical analysis was performed in STATA 16.0. STATAsuggested: (Stata, …SciScore for 10.1101/2020.09.10.20191841: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Antibodies Sentences Resources A Rapid Immunoglobulin Test Cassette was used to detect the presence of IgM and IgG antibodies to the ‘spike’ protein, thereby providing evidence for previous infection with SARS-CoV-2. SureScreen Diagnostics COVID-19 IgG/IgM Rapid Test Cassettes, the necessary equipment and detailed instructions were sent to participants’ home address. IgGsuggested: NoneSoftware and Algorithms Sentences Resources Statistical analysis: Statistical analysis was performed in STATA 16.0. STATAsuggested: (Stata, RRID:SCR_012763)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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