Retrospective clinical evaluation of 4 lateral flow assays for the detection of SARS-CoV-2 IgG

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Abstract

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  1. SciScore for 10.1101/2020.07.01.20129882: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    Institutional Review Board Statementnot detected.
    Randomizationnot detected.
    BlindingBoth readers were essentially blinded, in that the sample metadata (time to disease onset and Abbott results) were not revealed until reading was complete.
    Power Analysisnot detected.
    Sex as a biological variablenot detected.

    Table 2: Resources

    Antibodies
    SentencesResources
    Among these 105 specimens, there were 27 from individuals with a history of seasonal coronavirus infection (as determined by a syndromic respiratory PCR test) within 3 years prior to collection (HKU1, n = 13; NL63, n = 6; OC43, n = 6; 229E, n = 2), and 4 specimens reactive for rheumatoid factor, HIV-1 antibody, HAV total antibody, HBV core total …