Ag nanoparticles-based antimicrobial polycotton fabrics to prevent the transmission and spread of SARS-CoV-2
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Abstract
Pathogens (bacteria, fungus and virus) are becoming a potential threat to the health of human beings and environment worldwide. They widely exist in the environment, with characteristics of variety, spreading quickly and easily causing adverse reactions. In this work, an Ag-based material is used to be incorporated and functionalized in polycotton fabrics using pad-dry-cure method. This composite proved to be effective for inhibiting the SARS-CoV-2 virus, decreasing the number of replicates in 99.99% after an incubation period of 2 minutes. In addition, it caused 99.99% inhibition of the pathogens S. aureus , E. coli and C. albicans , preventing cross-infections and does not cause allergies or photoirritation processes, demonstrating the safety of its use.
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SciScore for 10.1101/2020.06.26.152520: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement not detected. Randomization not detected. Blinding Therefore, a unicentric, blind, comparative clinical study to assess the photoirritating and photosensitizing potential was also conducted, with the aim of proving the absence of the irritating potential of the product applied to the skin when exposed to ultraviolet radiation. Power Analysis not detected. Sex as a biological variable not detected. Cell Line Authentication not detected. Table 2: Resources
Experimental Models: Cell Lines Sentences Resources Then, they were plated onto tissue cultures of Vero CCL-81 cells. Vero CCL-81suggested: NoneAs control, the viral suspension was incubated in media without supplementation, … SciScore for 10.1101/2020.06.26.152520: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement not detected. Randomization not detected. Blinding Therefore, a unicentric, blind, comparative clinical study to assess the photoirritating and photosensitizing potential was also conducted, with the aim of proving the absence of the irritating potential of the product applied to the skin when exposed to ultraviolet radiation. Power Analysis not detected. Sex as a biological variable not detected. Cell Line Authentication not detected. Table 2: Resources
Experimental Models: Cell Lines Sentences Resources Then, they were plated onto tissue cultures of Vero CCL-81 cells. Vero CCL-81suggested: NoneAs control, the viral suspension was incubated in media without supplementation, with samples collected at 2 and 5 min used to infect Vero cells on the same plate The plate was incubated for 2 h at 37 °C, 5% CO2 for viral adsorption, and after this period, 166.6 μL of DMEM High Glucose medium containing 12% fetal bovine serum were added to each well, making to a final volume of 1 mL of medium/well containing 2% serum. Verosuggested: NoneSoftware and Algorithms Sentences Resources 67%Polyester / 33% cotton) purchased from local suppliers (São Carlos/SP, Brazil) was used for the application purpose. Polyestersuggested: (Polyester, RRID:SCR_003602)Morphologies of the composites were analyzed by Field Emission Scanning Electron Microscopy (FE-SEM) on a FEI instrument (Model Inspect F50) operating at 1 kV. Field Emission Scanningsuggested: (Hitachi S4700 Field Emission Scanning Electron Microscope, RRID:SCR_020019)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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