Randomized Re-Opening of Training Facilities during the COVID-19 pandemic
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Abstract
Background
Most countries closed training facilities during the COVID-19 pandemic. This may have negative consequences for people’s health and wellbeing. We investigated SARS-CoV-2 virus transmission and COVID-19 disease attributable to training facilities.
Methods
We randomized members 18 to 64 years with no COVID-19 relevant comorbidities randomized Five training facilities in Oslo, Norway to access or no access to their training facility. Facilities were opened from May 22, 2020 for individuals randomized to training, applying increased social distancing (1 meter for floor exercise, 2 meters for high-intensity classes), enhanced hand and surface hygiene. Locker rooms were open, showers and saunas were closed. We measured SARS-CoV-2 PCR status by self-administered naso-, oropharyngeal and sputum sampling after two weeks and clinical disease by linkage to electronic patient records after three weeks.
Results
3,764 individuals were randomized and included in analyses; 1,896 in the training and 1,868 in no-training arms. In the training arm, 81.8% trained at least once at the facilities, and 38.5% trained ≥six times. Out of 3,016 individuals who returned the SARS-CoV-2 PCR tests (80.5%), there was one positive test. The positive individual was randomized to training, but had not used the facility before testing day. Contact tracing revealed the workplace as transmission source. A total of 106 individuals (2.8%) had outpatient hospital visits, and six individuals were admitted to hospital during the three weeks after intervention start, with no differences between arms. There were no outpatient visits or hospital admissions due to COVID-19 in either group.
Conclusions
Provided good hygiene and social distancing measures, there was no increased COVID-19 spread at training facilities. NCT04406909
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SciScore for 10.1101/2020.06.24.20138768: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement Consent: All eligible individuals were informed about the nature of the trial, and provided consent before randomisation.
IRB: The study was approved by the Regional Ethical Committee of South-East Norway and the data protection officers at participating sites.Randomization not detected. Blinding not detected. Power Analysis For a power of 90% with an alpha of 0.05, we planned to include at least 1,696 individuals in each arm. Sex as a biological variable not detected. Table 2: Resources
Antibodies Sentences Resources Participants with insufficient quality or quantity of the dried blood spot sample or with test results close to a predefined cut-off for positivity … SciScore for 10.1101/2020.06.24.20138768: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement Consent: All eligible individuals were informed about the nature of the trial, and provided consent before randomisation.
IRB: The study was approved by the Regional Ethical Committee of South-East Norway and the data protection officers at participating sites.Randomization not detected. Blinding not detected. Power Analysis For a power of 90% with an alpha of 0.05, we planned to include at least 1,696 individuals in each arm. Sex as a biological variable not detected. Table 2: Resources
Antibodies Sentences Resources Participants with insufficient quality or quantity of the dried blood spot sample or with test results close to a predefined cut-off for positivity (“borderline” results), were asked to provide a venous serum sample for analysis on Roche’s platform for SARS-CoV2 antibodies (Elecsys® Anti-SARS-CoV-2). SARS-CoV2suggested: NoneAnti-SARS-CoV-2suggested: NoneResults from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.Results from TrialIdentifier: We found the following clinical trial numbers in your paper:
Identifier Status Title NCT04406909 Active, not recruiting Rapid-Cycle Re-Implementation of TRAining Facilities in Norw… Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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SciScore for 10.1101/2020.06.24.20138768: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement All eligible individuals were informed about the nature of the trial , and provided consent before randomization . Randomization Methods: We randomized members 18 to 64 years with no COVID-19 relevant comorbidities randomized Five training facilities in Oslo, Norway to access or no access to their training facility. Blinding not detected. Power Analysis For a power of 90 % with an alpha of 0.05 , we planned to include at least 1,696 individuals in each arm . Sex as a biological variable There were 1,929 female and 1,835 male participants , the majority was between 20 and 50 years old. Table 2: Resources
Antibodies Sentences Resources A commercially … SciScore for 10.1101/2020.06.24.20138768: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement All eligible individuals were informed about the nature of the trial , and provided consent before randomization . Randomization Methods: We randomized members 18 to 64 years with no COVID-19 relevant comorbidities randomized Five training facilities in Oslo, Norway to access or no access to their training facility. Blinding not detected. Power Analysis For a power of 90 % with an alpha of 0.05 , we planned to include at least 1,696 individuals in each arm . Sex as a biological variable There were 1,929 female and 1,835 male participants , the majority was between 20 and 50 years old. Table 2: Resources
Antibodies Sentences Resources A commercially available rapid self-sampling kit , for dried blood spots for testing for SARSCoV-2 antibodies , will be mailed to all participants between 3 and 4 weeks after study start , and will be mailed back in a prepaid envelope. SARSCoV-2suggested: NoneFuture long-term secondary project endpoints will include the proportion of individuals with SARS-CoV-2 antibodies in the two study arms after 30 days; comparison of ICU admission and ventilator treatment; and death of COVID-19 after three months . SARS-CoV-2suggested: (Sino Biological Cat# 40143-R019, AB_2827973)Software and Algorithms Sentences Resources ( StataCorp LLC , College Station , TX . ) The study was approved by the Regional Ethical Committee of South-East Norway and the data protection officers at participating sites . StataCorpsuggested: (Stata, SCR_012763)Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.
Results from OddPub: We did not find a statement about open data. We also did not find a statement about open code. Researchers are encouraged to share open data when possible (see Nature blog).
About SciScore
SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore is not a substitute for expert review. SciScore checks for the presence and correctness of RRIDs (research resource identifiers) in the manuscript, and detects sentences that appear to be missing RRIDs. SciScore also checks to make sure that rigor criteria are addressed by authors. It does this by detecting sentences that discuss criteria such as blinding or power analysis. SciScore does not guarantee that the rigor criteria that it detects are appropriate for the particular study. Instead it assists authors, editors, and reviewers by drawing attention to sections of the manuscript that contain or should contain various rigor criteria and key resources. For details on the results shown here, including references cited, please follow this link.
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