Seroprevalence of Herpes simplex virus Type-1 IgG antibodies among pregnant women with recurrent abortions

Herpes Simplex Virus Type - 1 (HSV-1) is a large, enveloped DNA virus that has a relationship with socioeconomic background. The virus can transmitted through direct contact with infected skin lesions or body fluids. Children may show asymptomatic or mucocutaneous vesicular eruptions, herpetic gingivostomatitis, acute herpetic pharyngotonsillitis, herpes labialis, herpes encephalitis, eczema herpeticum, and herpetic whitlow may occur. In the last few years the prevalence of HSV-1 infection increases progressively, so, the main aim of this study is to study the seroprevalence of herpes simplex virus type-1 IgG antibodies among pregnant women with recurrent abortions. The study confirmed a 29 (58%) were positive HSV-1-IgG and 21 (42%) were negative among cases (pregnant women) while 25 (100%) in control subject were negatives, and the possible risk factors i.e. age, Abortion, Blood transfusion, Contraceptive, Rash, have been examined in this study and showed no effect except previous history of TORCH test examination., The study settled that more than half of the pregnant women were found to be infected, and we recommended using both ELISA (IgM and IgG) and molecular techniques for detection, diagnosis and monitoring of viral infection.