<xhtml:span xmlns:xhtml="http://www.w3.org/1999/xhtml" xml:lang="en">First Italian case of Serratia ficaria infection in a woman with obstructive pancreatitis and review of the literature. </xhtml:span>
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Introduction: Serratia ficaria, is a Gram-negative rod first identified in 1979 in the fig tree ecosystem. Since then, Serratia ficaria has been occasionally isolated from human specimens. According to literature, Serratia ficaria is an opportunistic pathogen that rarely affects human, when infection occurs it can lead to different clinical conditions, including gallbladder empyema, lithiasis, ophthalmitis, leg ulceration, respiratory infections. Case presentation: We report the case of a 66-year-old woman in whom Serratia ficaria was the causative agent of acute obstructive jaundice. The woman was treated empirically with ceftriaxone and metronidazole before sphincterotomy.Serratia ficaria was isolated from bile samples collected by Endoscopic Retrograde Cholangiopancreatography (ERCP). Conclusion: Serratia ficaria causes mild infections in most cases, however, severe infections such as soft tissue infections or septicemia are reported in the literature. In this case, ERCP was crucial in the diagnosis and treatment of the patient, which favorably resolved the infection.
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The work presented is clear and the arguments well formed. This study would be a valuable contribution to the existing literature.
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Comments to Author
Please ONLY put comments for the Author(s) in here This article is a brief presentation on the first reported Italian case of pancreatitis caused by Serratia ficaria in a patient. A literature review of similar cases reported elsewhere is included owing to a paucity of information on human infections caused by S. ficaria which is normally found in figs and insects that pollinate fig trees. This article furthers our understanding about the association of S. ficaria with human infections. The authors clearly defined the problem, stated their objectives and shared their findings and conclusions. Coverage of the subject is well-organized. The authors provided a relatively comprehensive review of the published literature including the search criteria used. The data are valid, and study …
Comments to Author
Please ONLY put comments for the Author(s) in here This article is a brief presentation on the first reported Italian case of pancreatitis caused by Serratia ficaria in a patient. A literature review of similar cases reported elsewhere is included owing to a paucity of information on human infections caused by S. ficaria which is normally found in figs and insects that pollinate fig trees. This article furthers our understanding about the association of S. ficaria with human infections. The authors clearly defined the problem, stated their objectives and shared their findings and conclusions. Coverage of the subject is well-organized. The authors provided a relatively comprehensive review of the published literature including the search criteria used. The data are valid, and study approach was appropriate. The results will be useful to practitioners and researchers. Data summarizing published cases including clinical information and history of fig consumption was representative of prior scholarship. Regarding conclusions, please address comments on two statements that were over generalizations: At the population level, Serratia ficaria infection is prevalent in countries where fresh fig consumption is high, such as California and France, suggesting that the fig ecosystem may beis involved in the spread of Serratia ficaria to humans This case report is emblematic in describing the increasing role of the environment and climate change in the transmission of emerging pathogens to humans [8,9] The article is well written overall and appropriate in length. There were a few grammatical errors and several spelling errors, particularly in the References.
Please rate the quality of the presentation and structure of the manuscript
Satisfactory
To what extent are the conclusions supported by the data?
Strongly support
Do you have any concerns of possible image manipulation, plagiarism or any other unethical practices?
No
Is there a potential financial or other conflict of interest between yourself and the author(s)?
No
If this manuscript involves human and/or animal work, have the subjects been treated in an ethical manner and the authors complied with the appropriate guidelines?
Yes
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Comments to Author
1. Abstract--> introduction - first paragraph, last line: please specify the type or location of "lithiasis". 4. Introduction, first paragraph: please put full name of "B. penes" for the first time. 5. Case Presentation--> Diagnostic assessments, first line: please remove the word "treatable" which does not make any sense, second line: put numeric pain scale - 7/10, line three:remove the word "declivitous" line four: please mention which imaging modality over abdomen showed biliary duct dilation and pancreatitis line five: mention what part the lithiasis was confirmed with Ultrasound line eight: please put full forms of K2EDTA, BD and OU in the same paragraph - please put full forms for CHROMID, FC and MALDI_TOF 5. Case Presentation-->therapeutic interventions: please remove word 'die" and …
Comments to Author
1. Abstract--> introduction - first paragraph, last line: please specify the type or location of "lithiasis". 4. Introduction, first paragraph: please put full name of "B. penes" for the first time. 5. Case Presentation--> Diagnostic assessments, first line: please remove the word "treatable" which does not make any sense, second line: put numeric pain scale - 7/10, line three:remove the word "declivitous" line four: please mention which imaging modality over abdomen showed biliary duct dilation and pancreatitis line five: mention what part the lithiasis was confirmed with Ultrasound line eight: please put full forms of K2EDTA, BD and OU in the same paragraph - please put full forms for CHROMID, FC and MALDI_TOF 5. Case Presentation-->therapeutic interventions: please remove word 'die" and replace it with "day". And also mention, how many days patient received antibiotics. in the second last line: please put full form of ROCC 7. Discussion --> line 15: please specify the type or location of of lithiasis
Please rate the quality of the presentation and structure of the manuscript
Good
To what extent are the conclusions supported by the data?
Strongly support
Do you have any concerns of possible image manipulation, plagiarism or any other unethical practices?
No
Is there a potential financial or other conflict of interest between yourself and the author(s)?
No
If this manuscript involves human and/or animal work, have the subjects been treated in an ethical manner and the authors complied with the appropriate guidelines?
Yes
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