L-bodies are RNA–protein condensates driving RNA localization in Xenopus oocytes
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Abstract
In Xenopus oocytes, RNAs required for proper germ layer patterning localize to the vegetal cytoplasm in RNP granules, which we have termed localization bodies (L-bodies). In this work, we find that L-bodies are large, biomolecular condensates composed of a nondynamic mRNA-containing substructure enmeshed in a dynamic protein-containing layer.
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Excerpt
Joining the phase separated party: Oocytes have multiphasic Localization bodies
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