Assessing the transition of COVID-19 burden towards the young population while vaccines are rolled out in China*
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SciScore for 10.1101/2021.10.14.21265032: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
NIH rigor criteria are not applicable to paper type.Table 2: Resources
No key resources detected.
Results from OddPub: Thank you for sharing your code and data.
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:Our findings should be interpreted by considering the following limitations. First, we assumed that vaccine protection lasted longer than the time of our simulations (1 year). Recent immunological studies have shown that the neutralising antibody titres of inactivated vaccines decline to a low level at 6 months after the second vaccine dose[60, 61], which may indicate waning of vaccine efficacy. However, the correlation with protection …
SciScore for 10.1101/2021.10.14.21265032: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
NIH rigor criteria are not applicable to paper type.Table 2: Resources
No key resources detected.
Results from OddPub: Thank you for sharing your code and data.
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:Our findings should be interpreted by considering the following limitations. First, we assumed that vaccine protection lasted longer than the time of our simulations (1 year). Recent immunological studies have shown that the neutralising antibody titres of inactivated vaccines decline to a low level at 6 months after the second vaccine dose[60, 61], which may indicate waning of vaccine efficacy. However, the correlation with protection from SARS-CoV-2 infection has yet to be proven. Second, we estimated the disease burden potentially caused by the importation of Delta variant infections in the absence or presence of NPIs. The impact of NPIs has been modelled through a simple reduction in transmissibility occurring homogenously with age. We still lack evidence regarding whether this is the case or whether NPIs lead to age-related effects. Moreover, our analysis is not suited to pinpoint which NPIs need to be performed to reach the considered levels of transmission reduction. Further studies exploring this direction are required. In conclusion, in the absence of NPIs, the importation of Delta variant infections could lead to widespread transmission and substantial disease burden in mainland China, even with vaccination coverage as high as 97% of those aged ≥12 years. Our findings highlight the need to strengthen vaccination efforts by simultaneously extending the target age groups of the vaccination campaign, and elevating VE via booster vaccination and developing new highly ef...
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We found bar graphs of continuous data. We recommend replacing bar graphs with more informative graphics, as many different datasets can lead to the same bar graph. The actual data may suggest different conclusions from the summary statistics. For more information, please see Weissgerber et al (2015).
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a protocol registration statement.
Results from scite Reference Check: We found no unreliable references.
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