Mitochondrial DNA oxidation propagates autoimmunity by enabling plasmacytoid dendritic cells to induce TFH differentiation

Hongxu Xian
Kosuke Watari
Masafumi Ohira
Jonathan S. Brito
Peng He
Janset Onyuru
Elina I. Zuniga
Hal M. Hoffman
Michael Karin

Read the full article

Listed in

This article is not in any list yet, why not save it to one of your lists.

Log in to save this article

Abstract

No abstract available

Version published to 10.1038/s41590-025-02179-7
Jun 17, 2025
Version published to 10.21203/rs.3.rs-5194985/v1 on Research Square
Oct 14, 2024

TH5487 specifically targets NLRP3 in FCAS patients resistant to MCC950

This article has 13 authors:
1. Angela Lackner
2. Lemuel Leonidas
3. Alijah Macapagal
4. Hannah Lee
5. Huilin Xu
6. Yanfei Qiu
7. Melissa Campos
8. Julia E. Cabral
9. Janset Onyuru
10. Sanika Kulkarni
11. Lauren V. Albrecht
12. Hal M. Hoffman
13. Reginald McNulty
This article has no evaluationsLatest version Jun 9, 2025
Guanylate-Binding Proteins Promote Host Defense Against Leishmania major by Balancing iNOS/Arg-1 in Myeloid Cells

This article has 12 authors:
1. Lucy Fry
2. Het Adhvaryu
3. Hayden Roys
4. Anne Bowlin
5. Gopinath Venugopal
6. Jordan T. Bird
7. Charity Washam
8. Masahiro Yamamoto
9. Jörn Coers
10. Stephanie Byrum
11. Daniel Voth
12. Tiffany Weinkopff
This article has no evaluationsLatest version Jun 30, 2025
The lysosomal carrier SLC29A3 supports anti-bacterial signaling and promotes autophagy by activating TRPML1 in mouse dendritic cells

This article has 6 authors:
1. Daniel J. Netting
2. Cynthia López-Haber
3. Zachary Hutchins
4. José A. Martina
5. Rosa Puertollano
6. Adriana R. Mantegazza
This article has no evaluationsLatest version Jun 17, 2025