Structure of a lasso peptide bound ETB receptor provides insights into the mechanism of GPCR inverse agonism

  1. Wataru Shihoya
  2. Hiroaki Akasaka
  3. Peter A. Jordan
  4. Anna Lechner
  5. Bethany K. Okada
  6. Gabriella Costa Machado da Cruz
  7. Fumiya K. Sano
  8. Tatsuki Tanaka
  9. Ryo Kawahara
  10. Rajan Chaudhari
  11. Hiroko Masamune
  12. Mark J. Burk
  13. Osamu Nureki
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  1. Version published to 10.1038/s41467-025-57960-x
  2. Version published to 10.21203/rs.3.rs-3824116/v1 on Research Square
  3. Version published to 10.1101/2023.12.30.573741 on bioRxiv