Inhibitory regulation of calcium transients in prefrontal dendritic spines is compromised by a nonsense Shank3 mutation

  1. Farhan Ali
  2. Ling-Xiao Shao
  3. Danielle M. Gerhard
  4. Katherine Sweasy
  5. Santosh Pothula
  6. Christopher Pittenger
  7. Ronald S. Duman
  8. Alex C. Kwan

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Abstract

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  1. Version published to 10.1038/s41380-020-0708-6
  2. preLights

    Excerpt

    Don’t forget the interneurons! Ali et al. find reduced dendritic inhibition by Shank3-mutant interneurons in the prefrontal cortex is to blame for dendritic calcium dysregulation.

  3. Version published to 10.1101/2020.01.07.894832 on bioRxiv