Intracellular Pocket Conformations Determine Signaling Efficacy through the μ Opioid Receptor

David A. Cooper
Joseph DePaolo-Boisvert
Stanley A. Nicholson
Barien Gad
David D. L. Minh

Read the full article

Discuss this preprint

Start a discussion What are Sciety discussions?

Listed in

Reading List (BiophysicsColab)

Log in to save this article

Abstract

No abstract available

Version published to 10.1021/acs.jcim.4c01437
Jan 17, 2025
Version published to 10.1101/2024.04.03.588021 on bioRxiv
Apr 3, 2024

Spatiotemporal Modeling of GPCR Signaling: The Role of Endosomal Dynamics and Receptor Recycling

This article has 9 authors:
1. Chloé Weckel
2. Juliette Gourdon
3. Léo Darrigade
4. Vinesh Jugnarain
5. Pascale Crépieux
6. Eric Reiter
7. Frédéric Jean-Alphonse
8. Stefan Haar
9. Romain Yvinec
This article has no evaluationsLatest version May 4, 2026
Conformational Preference Classification of Integrin-Binding Ligands Using Free Energy Perturbation

This article has 8 authors:
1. Martin Vögele
2. Rezvan Shahoei
3. Loukas Petridis
4. Jing Li
5. Fu-Yang Lin
6. Lingle Wang
7. Timothy A. Springer
8. Jeremie Vendome
This article has no evaluationsLatest version Apr 30, 2026
Buprenorphine Restricts the Conformational Landscape of the μ-Opioid Receptor

This article has 5 authors:
1. Simone Aureli
2. Maria Bzowka
3. Nicola Piasentin
4. Massimo Fuss
5. Francesco Luigi Gervasio
This article has no evaluationsLatest version Jun 16, 2026