2008 financial crisis versus 2020 economic fallout: how COVID-19 might influence fertility treatment and live births

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Abstract

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  1. SciScore for 10.1101/2020.10.18.20214650: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    Institutional Review Board Statementnot detected.
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.
    Sex as a biological variablenot detected.

    Table 2: Resources

    No key resources detected.


    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).


    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    We note several limitations of our study. We evaluated population health outcomes and economic trends and did not account for variations at regional or subnational levels, which may mask variations particularly as the percentage of children born via assisted conception varies from high levels in some states such as Massachusetts (4.8%) to low in Puerto Rico (0.2%)30. For reasons of data availability and definitions we utilised total treatment cycles to develop our growth estimates, thereby allowing for variations in clinical practice and contextualisation of the 2008 financial crisis over two decades. We are unaware of any other reasons for the observed plateau, with the resumption of growth in 2012 aligning with other improvements in macroeconomic indicators. We have assumed an equivalent economic challenge due to COVID-19 as observed in 2008, however, we have performed sensitivity analyses for both a less or more severe impact and the true estimate on cycles and live births is likely to lie between these two extremes. Our prediction methods assume that past activity is a reliable indicator of future activity; we discuss these assumptions and show our predictions are not sensitive to them in Supplementary Material. Lastly, our estimates of live-birth reflect current reported success rates for all treatments performed within 12 months of the initiated stimulation cycle as per CDC and SART, we acknowledge that additional frozen embryo transfers may occur beyond this time-frame...

    Results from TrialIdentifier: No clinical trial numbers were referenced.


    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.


    Results from JetFighter: We did not find any issues relating to colormaps.


    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • No funding statement was detected.
    • No protocol registration statement was detected.

    About SciScore

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