Clinical trial protocols of repurposed prophylaxis for COVID-19: A review

This article has been Reviewed by the following groups

Read the full article See related articles

Abstract

No abstract available

Article activity feed

  1. SciScore for 10.1101/2020.05.30.20117937: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    Institutional Review Board Statementnot detected.
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.
    Sex as a biological variablenot detected.

    Table 2: Resources

    No key resources detected.


    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).


    Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.

    Results from TrialIdentifier: We found the following clinical trial numbers in your paper:

    IdentifierStatusTitle
    NCT04344600RecruitingPeginterferon Lambda-1a for the Prevention and Treatment of …
    NCT04321174RecruitingCOVID-19 Ring-based Prevention Trial With Lopinavir/Ritonavi…
    NCT04364022RecruitingEfficacy of Pragmatic Same-day COVID-19 Ring Prophylaxis for…
    NCT04328285Active, not recruitingChemoprophylaxis of SARS-CoV-2 Infection (COVID-19) in Expos…
    NCT04343248RecruitingTrial to Evaluate the Efficacy and Safety of Nitazoxanide (N…
    NCT04359680Active, not recruitingTrial to Evaluate the Efficacy and Safety of Nitazoxanide (N…
    NCT04312243Active, not recruitingNO Prevention of COVID-19 for Healthcare Providers
    NCT04337918CompletedNitric Oxide Releasing Solutions to Prevent and Treat Mild/M…
    NCT04323800RecruitingConvalescent Plasma to Stem Coronavirus (CSSC-001)
    NCT04328441Active, not recruitingReducing Health Care Workers Absenteeism in Covid-19 Pandemi…
    NCT04327206RecruitingBCG Vaccination to Protect Healthcare Workers Against COVID-…
    NCT04348370RecruitingBCG Vaccine for Health Care Workers as Defense Against COVID…
    NCT04350931Not yet recruitingApplication of BCG Vaccine for Immune-prophylaxis Among Egyp…
    NCT04362124WithdrawnPerformance Evaluation of BCG Vaccination in Healthcare Pers…
    NCT04353518RecruitingClinical Trial to Evaluate Mycobacterium w in Preventing COV…
    NCT04357028SuspendedMeasles Vaccine in HCW
    NCT04360122Not yet recruitingLevamisole and Isoprinosine in Immune-prophylaxis of Egyptia…
    NCT04344379SuspendedPrevention of SARS-CoV-2 in Hospital Workers s Exposed to th…
    NCT04354597Not yet recruitingHydroxychloroquine and Azithromycin as Prophylaxis for Healt…
    NCT04334928RecruitingRandomized Clinical Trial for the Prevention of SARS-CoV-2 I…
    NCT04340349Enrolling by invitationLow-dose Hydroxychloroquine and Bromhexine: a Novel Regimen …


    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.


    Results from JetFighter: We did not find any issues relating to colormaps.


    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    About SciScore

    SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore checks for the presence and correctness of RRIDs (research resource identifiers), and for rigor criteria such as sex and investigator blinding. For details on the theoretical underpinning of rigor criteria and the tools shown here, including references cited, please follow this link.