Sensitive on-site detection of SARS-CoV-2 by ID NOW COVID-19
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SciScore for 10.1101/2021.04.18.21255688: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics not detected. Sex as a biological variable not detected. Randomization Furthermore, 40 swab samples taken from various healthy persons every second day and intermittently positive controls were measured to see whether randomly taken specimens give false-positive results. Blinding not detected. Power Analysis not detected. Cell Line Authentication not detected. Table 2: Resources
Experimental Models: Cell Lines Sentences Resources Finally, cell culture supernatants of a reference strain (SARS-CoV-2/Italy-INMI1, kindly provided by Antonino DiCaro via the GHSAG network), the B.1.1.7 variant (Robert Koch Institute [RKI] isolate), the B.1.351 SA variant (kindly provided by Thorsten Wolff, RKI) and the Brazil … SciScore for 10.1101/2021.04.18.21255688: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics not detected. Sex as a biological variable not detected. Randomization Furthermore, 40 swab samples taken from various healthy persons every second day and intermittently positive controls were measured to see whether randomly taken specimens give false-positive results. Blinding not detected. Power Analysis not detected. Cell Line Authentication not detected. Table 2: Resources
Experimental Models: Cell Lines Sentences Resources Finally, cell culture supernatants of a reference strain (SARS-CoV-2/Italy-INMI1, kindly provided by Antonino DiCaro via the GHSAG network), the B.1.1.7 variant (Robert Koch Institute [RKI] isolate), the B.1.351 SA variant (kindly provided by Thorsten Wolff, RKI) and the Brazil TY7-503 variant of the P.1 lineage (hCoV-19/Japan/TY7-503/2021, kindly provided by Takaji Wakita, National Institute of Infectious Diseases, Japan, via the GHSAG network) grown in Vero E6 cells were used to test whether the ID NOW COVID-19 test detects these variants with a similar sensitivity as that for the SARS-CoV-2 variants circulating during the first months of the pandemic. Vero E6suggested: NoneRecombinant DNA Sentences Resources Finally, cell culture supernatants of a reference strain (SARS-CoV-2/Italy-INMI1, kindly provided by Antonino DiCaro via the GHSAG network), the B.1.1.7 variant (Robert Koch Institute [RKI] isolate), the B.1.351 SA variant (kindly provided by Thorsten Wolff, RKI) and the Brazil TY7-503 variant of the P.1 lineage (hCoV-19/Japan/TY7-503/2021, kindly provided by Takaji Wakita, National Institute of Infectious Diseases, Japan, via the GHSAG network) grown in Vero E6 cells were used to test whether the ID NOW COVID-19 test detects these variants with a similar sensitivity as that for the SARS-CoV-2 variants circulating during the first months of the pandemic. hCoV-19/Japan/TY7-503/2021suggested: NoneResults from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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