Monitoring populations at increased risk for SARS-CoV-2 infection in the community using population-level demographic and behavioural surveillance

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Abstract

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  1. SciScore for 10.1101/2021.09.02.21263017: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    NIH rigor criteria are not applicable to paper type.

    Table 2: Resources

    No key resources detected.


    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).


    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    The screening process demonstrated here has several limitations. First, low event numbers and smaller sample sizes reduce statistical power, reducing the chance of detecting true associations (false- negatives) and increasing the likelihood that the magnitude of “true” effects are inflated (false- positives).24 Increased statistical power using 28-day periods rather than fortnights more consistently detected associations with ethnicity in the core model and found more evidence of interactions. The screening process, however, detected the same characteristics using both time-periods, with earlier detection in most cases using fortnights. As there were no major differences and we aimed to identify associations most relevant to current positivity, the benefit of more regular estimates may outweigh the power gained from evaluating longer time-frames, although this will depend on event numbers. When events numbers are low, logistic regression can be biased and/or imprecise.25, 26 Sensitivity analyses using penalised regression techniques showed most coefficients were within the logistic regression confidence intervals, suggesting that, while there was some attenuation of estimates, for example for geographical regions in a few fortnights, the logistic regression models were not substantially overfitting. Multiple testing is an unavoidable limitation of our screening process. Doing many multiple independent tests increases the risk of false-positives;27 however, a priori the questi...

    Results from TrialIdentifier: We found the following clinical trial numbers in your paper:

    IdentifierStatusTitle
    ISRCTN21086382NANA


    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.


    Results from JetFighter: We did not find any issues relating to colormaps.


    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a protocol registration statement.

    Results from scite Reference Check: We found no unreliable references.


    About SciScore

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