Optimising health and economic impacts of COVID-19 vaccine prioritisation strategies in the WHO European Region: a mathematical modelling study

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Abstract

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  1. SciScore for 10.1101/2021.07.09.21260272: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    NIH rigor criteria are not applicable to paper type.

    Table 2: Resources

    No key resources detected.


    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).


    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    Strengths and limitations: While existing literature focuses on evaluating COVID-19 vaccine prioritisation in any particular city or country, our study is the first to investigate the impact of such strategies under different circumstances across a large region. We demonstrated that different age structures, contact patterns, and sizes of existing epidemics may affect the health and economic impacts of vaccination prioritisation strategies. Second, we built our analyses around realistic vaccine roll-out scenarios based on projecting the broad patterns in vaccine roll-out rates across the region. Third, we evaluated a wide range of age-prioritisation strategies, not only under different roll-out scenarios but also at different supply levels (e.g. 3%, 20%, 50% or 80% coverage). The results inform policy recommendations, providing the necessary details for continuous implementation. The models and analyses presented here have benefited from continuous input since late 2020 from the WHO Regional Office for Europe and technical advisors from many countries in the region. Fourth, we included additional decision-making metrics beyond mortality and morbidity, providing a more comprehensive assessment of the various trade-offs that need to be considered between outcomes.36 Fifth, we considered various vaccine profiles to account for uncertainty around vaccine characteristics. Last but not the least, new evidence about vaccine action, changes in vaccine supply constraints and the emerg...

    Results from TrialIdentifier: No clinical trial numbers were referenced.


    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.


    Results from JetFighter: We did not find any issues relating to colormaps.


    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    Results from scite Reference Check: We found no unreliable references.


    About SciScore

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