Validation of a combined ELISA to detect IgG, IgA and IgM antibody responses to SARS-CoV-2 in mild or moderate non-hospitalised patients
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Abstract
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SciScore for 10.1101/2020.11.30.20229732: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement IRB: For the specificity and sensitivity analysis residual samples were from commercial sources (BioIVT, approved by Western Institutional Review Board -
Consent: ; TCS Bioscience approved by The Diagnostics Investigational Review Board-IRB112015-01.1; anonymised normal samples provided by Plasma Services Group were collected with patient consent via an FDA registered blood establishment (registration number 3005275238)) and further residual samples collected in accordance with REC 2002/201; South Birmingham Research Ethics Service.Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
SciScore for 10.1101/2020.11.30.20229732: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement IRB: For the specificity and sensitivity analysis residual samples were from commercial sources (BioIVT, approved by Western Institutional Review Board -
Consent: ; TCS Bioscience approved by The Diagnostics Investigational Review Board-IRB112015-01.1; anonymised normal samples provided by Plasma Services Group were collected with patient consent via an FDA registered blood establishment (registration number 3005275238)) and further residual samples collected in accordance with REC 2002/201; South Birmingham Research Ethics Service.Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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