Age-related gene expression alterations by SARS-CoV-2 infection contribute to poor prognosis in elderly
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SciScore for 10.1101/2020.06.15.151761: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
NIH rigor criteria are not applicable to paper type.Table 2: Resources
Software and Algorithms Sentences Resources Identification of druggable targets: Finally, these genes identified above were screened for their druggability with FDA approved drugs using DGIdb website (http://dgidb.org). DGIdbsuggested: (DGIdb, RRID:SCR_006608)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:Limitation: Our study is limited by non-availability of large tissue specific transcriptomic datasets of …
SciScore for 10.1101/2020.06.15.151761: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
NIH rigor criteria are not applicable to paper type.Table 2: Resources
Software and Algorithms Sentences Resources Identification of druggable targets: Finally, these genes identified above were screened for their druggability with FDA approved drugs using DGIdb website (http://dgidb.org). DGIdbsuggested: (DGIdb, RRID:SCR_006608)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:Limitation: Our study is limited by non-availability of large tissue specific transcriptomic datasets of COVID19 patients across age groups, and with varying severity and from different populations to validate the hypothesis.
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- No funding statement was detected.
- No protocol registration statement was detected.
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