Simulated Identification of Silent COVID-19 Infections Among Children and Estimated Future Infection Rates With Vaccination
This article has been Reviewed by the following groups
Discuss this preprint
Start a discussion What are Sciety discussions?Listed in
- Evaluated articles (ScreenIT)
Abstract
Article activity feed
-
-
SciScore for 10.1101/2021.01.06.21249349: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
NIH rigor criteria are not applicable to paper type.Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:Limitations: Our results should be interpreted within the context of model limitations. First, we did not explicitly include the effects of non-pharmaceutical interventions, but instead calibrated the model to current estimates of the effective reproduction number which implicitly account for these effects.33 The relaxation of such …
SciScore for 10.1101/2021.01.06.21249349: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
NIH rigor criteria are not applicable to paper type.Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:Limitations: Our results should be interpreted within the context of model limitations. First, we did not explicitly include the effects of non-pharmaceutical interventions, but instead calibrated the model to current estimates of the effective reproduction number which implicitly account for these effects.33 The relaxation of such measures would increase the need for vigilant contact-tracing among unvaccinated populations. Given COVID-19 awareness and public health recommendations, we assumed that all symptomatic cases self-isolate within 24 hours of symptom onset. Despite this high rate of rapid self-isolation, our sensitivity analyses confirm that rapid contact-tracing will still be an important dimension of control even if child susceptibility is half that of adults. With vaccination of adults, we evaluated the impact of identifying silent infections only among children. However, our results should not be interpreted as excluding adults for identification of silent infections. Our focus on targeting children is largely motivated by current deliberations regarding the reopening of schools and the potential for ensuing elevated spread of COVID-19 through asymptomatic infections in this population. Simultaneously expanding identification of silent infections among young adults currently not prioritized for vaccination would contribute to earlier control of outbreaks. For the effect of vaccination, we parameterized the model with results of phase III clinical trials for vacci...
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
-
