S-Gene Target Failure as a Marker of Variant B.1.1.7 Among SARS-CoV-2 Isolates in the Greater Toronto Area, December 2020 to March 2021
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SciScore for 10.1101/2021.02.09.21251225: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics not detected. Sex as a biological variable not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:This study has a number of limitations. These data represent a sample from a region which has experienced high rates of COVID-19, and includes outbreak-related cases, and as such is not representative of the entire province. Nevertheless, the exponential …
SciScore for 10.1101/2021.02.09.21251225: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics not detected. Sex as a biological variable not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:This study has a number of limitations. These data represent a sample from a region which has experienced high rates of COVID-19, and includes outbreak-related cases, and as such is not representative of the entire province. Nevertheless, the exponential increase in case counts is cause for concern. Further, our approach to SGTF detection used all positive samples, including results with high Ct values where SGTF could be incidental. As such, our approach was likely not as specific a marker of B.1.1.7 as samples with lower Ct values (e.g., Ct values <30). In order to pre-emptively plan and implement public health measures to control COVID-19 through the spring, accurate and up-to-date early warning systems for new variants, including B.1.1.7, are essential across North America and the globe.
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- No funding statement was detected.
- No protocol registration statement was detected.
Results from scite Reference Check: We found no unreliable references.
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