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  1. Fragment-based discovery of a new class of inhibitors targeting mycobacterial tRNA modification

    This article has 17 authors:
    1. Sherine E Thomas
    2. Andrew J Whitehouse
    3. Karen Brown
    4. Sophie Burbaud
    5. Juan M Belardinelli
    6. Jasper Sangen
    7. Ramanuj Lahiri
    8. Mark Daben J Libardo
    9. Pooja Gupta
    10. Sony Malhotra
    11. Helena I M Boshoff
    12. Mary Jackson
    13. Chris Abell
    14. Anthony G Coyne
    15. Tom L Blundell
    16. Rodrigo Andres Floto
    17. Vítor Mendes

    Reviewed by preLights

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  2. Rapid discovery of synthetic DNA sequences to rewrite endogenous T cell circuits

    This article has 16 authors:
    1. Theodore L. Roth
    2. P. Jonathan Li
    3. Jasper F. Nies
    4. Ruby Yu
    5. Michelle L.T. Nguyen
    6. Youjin Lee
    7. Ryan Apathy
    8. Anna Truong
    9. Joseph Hiatt
    10. David Wu
    11. David N. Nguyen
    12. Daniel Goodman
    13. Jeffrey A. Bluestone
    14. Kole Roybal
    15. Eric Shifrut
    16. Alexander Marson

    Reviewed by preLights

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  3. Humans optimally anticipate and compensate for an uneven step during walking

    This article has 2 authors:
    1. Osman Darici
    2. Arthur D Kuo
    This article has been curated by 1 group:
    • Curated by eLife

      Evaluation Summary:

      This study provides experimental evidence supporting an energy optimality principle for walking over uneven terrain. Using a simple rimless wheel model of human walking, the authors previously predicted speed fluctuations to emerge when a step up or down when energy is minimized over the entire walking path. New experimental evidence provides evidence that both anticipatory and reactive adjustments used by the nervous system follow the predictions of an energy minimization principle. The predictive power of an energy-minimization principle during transient, non-steady state behavior is notable. Certain issues regarding the generalizability of the results to variable step lengths and timing, alternative optimality criteria, and limitations of the modeling assumptions should be clarified.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #3 agreed to share their name with the authors.)

    Reviewed by eLife, preLights

    This article has 6 evaluationsAppears in 2 listsLatest version Latest activity
  4. Tapping into non-English-language science for the conservation of global biodiversity

    This article has 63 authors:
    1. Tatsuya Amano
    2. Violeta Berdejo-Espinola
    3. Alec P. Christie
    4. Kate Willott
    5. Munemitsu Akasaka
    6. András Báldi
    7. Anna Berthinussen
    8. Sandro Bertolino
    9. Andrew J. Bladon
    10. Min Chen
    11. Chang-Yong Choi
    12. Magda Bou Dagher Kharrat
    13. Luis G. de Oliveira
    14. Perla Farhat
    15. Marina Golivets
    16. Nataly Hidalgo Aranzamendi
    17. Kerstin Jantke
    18. Joanna Kajzer-Bonk
    19. M. Çisel Kemahlı Aytekin
    20. Igor Khorozyan
    21. Kensuke Kito
    22. Ko Konno
    23. Da-Li Lin
    24. Nick Littlewood
    25. Yang Liu
    26. Yifan Liu
    27. Matthias-Claudio Loretto
    28. Valentina Marconi
    29. Philip A. Martin
    30. William H. Morgan
    31. Juan P. Narváez-Gómez
    32. Pablo Jose Negret
    33. Elham Nourani
    34. Jose M. Ochoa Quintero
    35. Nancy Ockendon
    36. Rachel Rui Ying Oh
    37. Silviu O. Petrovan
    38. Ana C. Piovezan-Borges
    39. Ingrid L. Pollet
    40. Danielle L. Ramos
    41. Ana L. Reboredo Segovia
    42. A. Nayelli Rivera-Villanueva
    43. Ricardo Rocha
    44. Marie-Morgane Rouyer
    45. Katherine A. Sainsbury
    46. Richard Schuster
    47. Dominik Schwab
    48. Çağan H. Şekercioğlu
    49. Hae-Min Seo
    50. Gorm Shackelford
    51. Yushin Shinoda
    52. Rebecca K. Smith
    53. Shan-dar Tao
    54. Ming-shan Tsai
    55. Elizabeth H. M. Tyler
    56. Flóra Vajna
    57. José Osvaldo Valdebenito
    58. Svetlana Vozykova
    59. Paweł Waryszak
    60. Veronica Zamora-Gutierrez
    61. Rafael D. Zenni
    62. Wenjun Zhou
    63. William J. Sutherland

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    This article has 1 evaluationAppears in 1 listLatest version Latest activity