Evaluated articles

Anti-biofilm efficacy of a medieval treatment for bacterial infection requires the combination of multiple ingredients

1. Jessica Furner-Pardoe
2. Blessing O. Anonye
3. Ricky Cain
4. John Moat
5. Catherine A. Ortori
6. Christina Lee
7. David A. Barrett
8. Christophe Corre
9. Freya Harrison

Reviewed by preLights

Combinatorial mutagenesis of rapidly evolving residues yields super-restrictor antiviral proteins

1. Rossana Colón-Thillet
2. Emily Hsieh
3. Laura Graf
4. Richard N. McLaughlin
5. Janet M. Young
6. Georg Kochs
7. Michael Emerman
8. Harmit S. Malik

Reviewed by preLights

Open science saves lives: lessons from the COVID-19 pandemic

1. Lonni Besançon
2. Nathan Peiffer-Smadja
3. Corentin Segalas
4. Haiting Jiang
5. Paola Masuzzo
6. Cooper Smout
7. Eric Billy
8. Maxime Deforet
9. Clémence Leyrat

Reviewed by ScreenIT, preLights

Molecular determinants of the Ska-Ndc80 interaction and their influence on microtubule tracking and force-coupling

1. Pim J Huis in 't Veld
2. Vladimir A Volkov
3. Isabelle D Stender
4. Andrea Musacchio
5. Marileen Dogterom

Reviewed by preLights

Intraspecific variation in thermal tolerance differs between tropical and temperate fishes

1. J.J.H. Nati
2. M.B.S. Svendsen
3. S. Marras
4. S.S. Killen
5. J.F. Steffensen
6. D.J. McKenzie
7. P. Domenici

Reviewed by preLights

Oxygen supply capacity in animals evolves to meet maximum demand at the current oxygen partial pressure regardless of size or temperature

1. Brad A. Seibel
2. Curtis Deutsch

Reviewed by preLights

An atlas of cortical arealization identifies dynamic molecular signatures

1. Aparna Bhaduri
2. Carmen Sandoval-Espinosa
3. Marcos Otero-Garcia
4. Irene Oh
5. Raymund Yin
6. Ugomma C. Eze
7. Tomasz J. Nowakowski
8. Arnold R. Kriegstein

Reviewed by preLights

Higher temperatures generically favour slower-growing bacterial species in multispecies communities

1. Simon Lax
2. Clare I. Abreu
3. Jeff Gore

Reviewed by preLights

Tamoxifen reduces inflammatory infiltration of neutrophils in the airways

1. Agustín Mansilla
2. Jaime Soto
3. Claudio Henríquez
4. Amber Philp
5. Marcus A. Mall
6. José Sarmiento
7. Carlos A. Flores

Reviewed by preLights

SIV and Mycobacterium tuberculosis synergy within the granuloma accelerates the reactivation pattern of latent tuberculosis

1. Collin R. Diedrich
2. Tara Rutledge
3. Pauline Maiello
4. Tonilynn M. Baranowski
5. Alexander G. White
6. H. Jacob Borish
7. Paul Karell
8. Forrest Hopkins
9. Jessica Brown
10. Sarah M. Fortune
11. JoAnne L. Flynn
12. Zandrea Ambrose
13. Philana Ling Lin

Reviewed by preLights

High-throughput functional analysis of lncRNA core promoters elucidates rules governing tissue specificity

1. Kaia Mattioli
2. Pieter-Jan Volders
3. Chiara Gerhardinger
4. James C. Lee
5. Philipp G. Maass
6. Marta Melé
7. John L. Rinn

Reviewed by preLights

Direct ETTIN-auxin interaction controls chromatin states in gynoecium development

1. André Kuhn
2. Sigurd Ramans Harborough
3. Heather M McLaughlin
4. Bhavani Natarajan
5. Inge Verstraeten
6. Jiří Friml
7. Stefan Kepinski
8. Lars Østergaard

Reviewed by preLights

Mechanisms underlying the cooperation between loss of epithelial polarity and Notch signaling during neoplastic growth in Drosophila

1. Rémi Logeay
2. Charles Géminard
3. Patrice Lassus
4. Miriam Rodríguez-Vázquez
5. Diala Kantar
6. Lisa Heron-Milhavet
7. Bettina Fischer
8. Sarah J. Bray
9. Jacques Colinge
10. Alexandre Djiane

Reviewed by preLights

Visualizing cellular and tissue ultrastructure using Ten-fold Robust Expansion Microscopy (TREx)

1. Hugo GJ Damstra
2. Boaz Mohar
3. Mark Eddison
4. Anna Akhmanova
5. Lukas C Kapitein
6. Paul W Tillberg

• Curated by eLife

  Evaluation Summary:

  This manuscript reports a robust and well-characterized expansion method that achieves 10X expansion with a single expansion step using a simple, easy-to-use protocol. The new protocol leads to an enabling methodology for super-resolution imaging of various sub-cellular structures and organelles and is likely to have a high impact.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #2 agreed to share their name with the authors.)

Reviewed by eLife, preLights

Precise genomic deletions using paired prime editing

1. Junhong Choi
2. Wei Chen
3. Chase C. Suiter
4. Choli Lee
5. Florence M. Chardon
6. Wei Yang
7. Anh Leith
8. Riza M. Daza
9. Beth Martin
10. Jay Shendure

Reviewed by preLights

Emergent RNA–RNA interactions can promote stability in a facultative phototrophic endosymbiosis

1. Benjamin H. Jenkins
2. Finlay Maguire
3. Guy Leonard
4. Joshua D. Eaton
5. Steven West
6. Benjamin E. Housden
7. David S. Milner
8. Thomas A. Richards

Reviewed by preLights

Systematic reconstruction of the cellular trajectories of mammalian embryogenesis

1. Chengxiang Qiu
2. Junyue Cao
3. Tony Li
4. Sanjay Srivatsan
5. Xingfan Huang
6. Diego Calderon
7. William Stafford Noble
8. Christine M. Disteche
9. Malte Spielmann
10. Cecilia B. Moens
11. Cole Trapnell
12. Jay Shendure

Reviewed by preLights

Spatial heterogeneity of cell-matrix adhesive forces predicts human glioblastoma migration

1. Rasha Rezk
2. Bill Zong Jia
3. Astrid Wendler
4. Ivan Dimov
5. Colin Watts
6. Athina E Markaki
7. Kristian Franze
8. Alexandre J Kabla

Reviewed by preLights

Depression of heart rate in fish at critically high temperatures is due to atrioventricular block

1. Jaakko Haverinen
2. Matti Vornanen

Reviewed by preLights

The nucleocytosolic O-fucosyltransferase SPINDLY affects protein expression and virulence in Toxoplasma gondii

1. Giulia Bandini
2. Carolina Agop-Nersesian
3. Hanke van der Wel
4. Msano Mandalasi
5. Hyun W. Kim
6. Christopher M. West
7. John Samuelson

Reviewed by preLights