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  1. Ripply1 and Gsc collectively suppress anterior endoderm differentiation from prechordal plate progenitors

    This article has 18 authors:
    1. Tao Cheng
    2. Xiang Liu
    3. Yang Dong
    4. Yi-Meng Tian
    5. Yan-Yi Xing
    6. Chen-Yi Chen
    7. Cong Liu
    8. Yun-Fei Li
    9. Ying Huang
    10. Ding-Hao Zhuo
    11. Xiao Xu
    12. Jing-Yun Luan
    13. Xin-Xin Fu
    14. Zi-Xin Jin
    15. Jing Mo
    16. Xiang Xu
    17. Hong-Qing Liang
    18. Peng-Fei Xu
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This study provides a useful analysis of the changes in chromatin organization and gene expression that occur during the differentiation of two cell types (anterior endoderm and prechordal plate) from a common progenitor in zebrafish, together with investigations into the molecular factors involved. Although the findings are consistent with previous work, the evidence presented appears to be incomplete and would benefit from more rigorous quantification of live imaging and Cre-Lox experiments, a stronger rationale and controls for experiments manipulating chromatin remodeling factors, and a strong justification for the explant model especially given differences between explant and whole embryo data. This work may be of interest to zebrafish developmental biologists investigating the mechanisms underlying specification.

    Reviewed by eLife, Review Commons

    This article has 13 evaluationsAppears in 2 listsLatest version Latest activity
  2. Single-cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma

    This article has 22 authors:
    1. Lise Finotto
    2. Basiel Cole
    3. Wolfgang Giese
    4. Elisabeth Baumann
    5. Annelies Claeys
    6. Maxime Vanmechelen
    7. Brecht Decraene
    8. Marleen Derweduwe
    9. Nikolina Dubroja Lakic
    10. Gautam Shankar
    11. Madhu Nagathihalli Kantharaju
    12. Jan Philipp Albrecht
    13. Ilse Geudens
    14. Fabio Stanchi
    15. Keith L. Ligon
    16. Bram Boeckx
    17. Diether Lambrechts
    18. Kyle Harrington
    19. Ludo Van Den Bosch
    20. Steven De Vleeschouwer
    21. Frederik De Smet
    22. Holger Gerhardt

    Reviewed by Review Commons

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity