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Inhibition of a lower potency target drives the anticancer activity of a clinical p38 inhibitor

This article has 10 authors:
1. Debanjan Bhattacharjee
2. Jaweria Bakar
3. Surbhi P. Chitnis
4. Erin L. Sausville
5. Kumar Dilip Ashtekar
6. Brianna E. Mendelson
7. Kaitlin Long
8. Joan C. Smith
9. David E. Heppner
10. Jason M. Sheltzer
This article has no evaluationsAppears in 1 listLatest version Oct 1, 2023
Allosteric substrate activation of SAMHD1 shapes deoxynucleotide triphosphate imbalances by interconnecting the depletion and biosynthesis of different dNTPs

This article has 3 authors:
1. Claudia McCown
2. Corey H. Yu
3. Dmitri N. Ivanov
This article has no evaluationsAppears in 1 listLatest version Nov 14, 2023
De novo purine metabolism is a metabolic vulnerability of cancers with low p16 expression

This article has 16 authors:
1. Naveen Kumar Tangudu
2. Raquel Buj
3. Hui Wang
4. Jiefei Wang
5. Aidan R. Cole
6. Apoorva Uboveja
7. Richard Fang
8. Amandine Amalric
9. Peter Sajjakulnukit
10. Maureen A. Lyons
11. Kristine Cooper
12. Nadine Hempel
13. Nathaniel W. Snyder
14. Costas A. Lyssiotis
15. Uma R. Chandran
16. Katherine M. Aird
This article has no evaluationsAppears in 1 listLatest version Sep 23, 2023