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  1. The cytoplasm of living cells can sustain transient and steady intracellular pressure gradients

    This article has 7 authors:
    1. Majid Malboubi
    2. Mohammad Hadi Esteki
    3. Malti B Vaghela
    4. Lulu IT Korsak
    5. Ryan J Petrie
    6. Emad Moeendarbary
    7. Guillaume Charras
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This important study combines imaginative and innovative experiments with a finite element modelling to demonstrate the relevance of poroelasticity in the mechanical properties of cells across physiologically relevant time and length scales. The authors present convincing evidence that cytosolic flows and pressure gradients can persist in cells with permeable membranes, generating spatially segregated influx and outflux zones. These findings are of interest to the cell biology and biophysics communities.

    Reviewed by eLife

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