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  1. Extracellular Perinexal Separation Is a Principal Determinant of Cardiac Conduction

    This article has 18 authors:
    1. William P. Adams
    2. Tristan B. Raisch
    3. Yajun Zhao
    4. Rafael Davalos
    5. Sarah Barrett
    6. D. Ryan King
    7. Chandra B. Bain
    8. Katrina Colucci-Chang
    9. Grace A. Blair
    10. Alexandra Hanlon
    11. Alicia Lozano
    12. Rengasayee Veeraraghavan
    13. Xiaoping Wan
    14. Isabelle Deschenes
    15. James W. Smyth
    16. Gregory S. Hoeker
    17. Robert G. Gourdie
    18. Steven Poelzing
    This article has no evaluationsAppears in 1 listLatest version
  2. GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway

    This article has 19 authors:
    1. Nicholas Hoppe
    2. Simone Harrison
    3. Sun-Hee Hwang
    4. Ziwei Chen
    5. Masha Karelina
    6. Ishan Deshpande
    7. Carl-Mikael Suomivuori
    8. Vivek R. Palicharla
    9. Samuel P. Berry
    10. Philipp Tschaikner
    11. Dominik Regele
    12. Douglas F. Covey
    13. Eduard Stefan
    14. Debora S. Marks
    15. Jeremy F. Reiter
    16. Ron O. Dror
    17. Alex S. Evers
    18. Saikat Mukhopadhyay
    19. Aashish Manglik
    This article has no evaluationsAppears in 1 listLatest version
  3. Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2

    This article has 19 authors:
    1. Huanyu Z. Li
    2. Ashley C. W. Pike
    3. Irina Lotsaris
    4. Gamma Chi
    5. Jesper S. Hansen
    6. Sarah C. Lee
    7. Karin E. J. Rödström
    8. Simon R. Bushell
    9. David Speedman
    10. Adam Evans
    11. Dong Wang
    12. Didi He
    13. Leela Shrestha
    14. Chady Nasrallah
    15. Nicola A. Burgess-Brown
    16. Robert J. Vandenberg
    17. Timothy R. Dafforn
    18. Elisabeth P. Carpenter
    19. David B. Sauer
    This article has no evaluationsAppears in 1 listLatest version
  4. Structure and dynamics of cholesterol-mediated aquaporin-0 arrays and implications for lipid rafts

    This article has 5 authors:
    1. Po-Lin Chiu
    2. Juan D Orjuela
    3. Bert L de Groot
    4. Camilo Aponte SantamarĂ­a
    5. Thomas Walz
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This manuscript aims to unravel the contribution of cholesterol to aquaporin-0 (AQP0) tetramer array formation within lens membranes. Compelling electron crystallography data are combined with solid molecular dynamics experiments to identify a specific cholesterol binding site of significance to protein clustering within lipid rafts. The important work advances our understanding of membrane biology and will be of broad interest to membrane transport biologists, biochemists, and structural biologists.

    Reviewed by eLife

    This article has 9 evaluationsAppears in 2 listsLatest version Latest activity