Review Commons

Latest preprint reviews

1. Opposing roles for lipocalins and a CD36 family scavenger receptor in apical extracellular matrix-dependent protection of narrow tube integrity

   This article has 10 authors:

   1. Alexandra C. Belfi
   2. Sage G. Aviles
   3. Rachel Forman-Rubinsky
   4. Hasreet K. Gill
   5. Jennifer D. Cohen
   6. Aleksandra Nawrocka
   7. Axelle Bourez
   8. Pierre van Antwerpen
   9. Patrick Laurent
   10. Meera V. Sundaram

   Reviewed by Review Commons

2. Translational buffering tunes gene expression in mice and humans

   This article has 4 authors:

   1. Shilpa Rao
   2. Aden Y Le
   3. Logan Persyn
   4. Can Cenik

   Reviewed by Review Commons

3. Trisomy 21 impairs synchronized activity and connectivity in developing human down syndrome cortical excitatory neuron networks

   This article has 8 authors:

   1. Manuel Peter
   2. Raquel Real
   3. Alessio Strano
   4. Hugh P. C. Robinson
   5. Mark A. Smith
   6. Samuel J. Barnes
   7. Vincenzo de Paola
   8. Frederick J. Livesey

   Reviewed by Review Commons

4. Microbiota impact Drosophila ageing via Acetobacter, Tachykinin, and TkR99D

   This article has 7 authors:

   1. Diana Marcu
   2. David R Sannino
   3. Anthony J Dornan
   4. Rita Ibrahim
   5. Atharv Kapoor
   6. Miriam Wood
   7. Adam J Dobson

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This important study demonstrates that in Drosophila melanogaster, tachykinin (Tk) expression is regulated by the microbiota. The authors present convincing evidence that axenic flies raised with no microbiota are longer-lived than conventionally reared animals, and that Tk expression and Tk receptors in the nervous system are required for this effect. They further test individual bacterial strains for their role in these effects and connect the effect to loss of lipid stores and suggest that FOXO may be involved in the phenotype, results that are of interest to the fields of environmental perception, host microbiome interactions, and geroscience.

     [Editors' note: this paper was reviewed by Review Commons.]

   Reviewed by eLife, Review Commons

5. Chronic replication stress-mediated genomic instability disrupts placenta development in mice

   This article has 4 authors:

   1. Mumingjiang Munisha
   2. Rui Huang
   3. Jordan Khan
   4. John C. Schimenti

   Reviewed by Review Commons

6. miR-184 modulates dilp8 to control developmental timing during normal growth conditions and in response to developmental perturbations

   This article has 4 authors:

   1. Jervis Fernandes
   2. Muhammed Naseem
   3. Ayisha Marwa MP
   4. Jishy Varghese

   Reviewed by Review Commons

7. The Ketogenic Diet Metabolite β-Hydroxybutyrate Promotes Mitochondrial Elongation via Deacetylation and Improves Autism-like Behavior in Zebrafish

   This article has 8 authors:

   1. Golam M. Uddin
   2. Rachel Lacroix
   3. Mashiat Zaman
   4. Iman Al Khatib
   5. Amit Jaiswal
   6. Jong M. Rho
   7. Deborah M. Kurrasch
   8. Timothy E. Shutt

   Reviewed by Review Commons

8. When mitochondria fall apart: Unbalanced mitochondrial segregation triggers loss of mtDNA in the absence of mitochondrial fusion

   This article has 8 authors:

   1. Lisa Dengler
   2. Francesco Padovani
   3. Bianca Lemke
   4. Rebecca Brugger
   5. Benedikt Westermann
   6. Boris Maček
   7. Kurt M. Schmoller
   8. Jennifer C. Ewald

   Reviewed by Review Commons

9. Interferon-β induction heterogeneity during KSHV infection is correlated to levels and activation of the transcription factors ATF2 and RelA, and not IRF3

   This article has 2 authors:

   1. Machika Kaku
   2. Marta Maria Gaglia

   Reviewed by Review Commons

10. Global molecular landscape of early MASLD progression in obesity

    This article has 21 authors:

    1. Qing Zhao
    2. William De Nardo
    3. Ruoyu Wang
    4. Yi Zhong
    5. Umur Keles
    6. Gabrielé Sakalauskaite
    7. Li Na Zhao
    8. Huiyi Tay
    9. Sonia Youhanna
    10. Mengchao Yan
    11. Ye Xie
    12. Youngrae Kim
    13. Sungdong Lee
    14. Rachel Liyu Lim
    15. Guoshou Teo
    16. Pradeep Narayanaswamy
    17. Paul R Burton
    18. Volker M Lauschke
    19. Hyungwon Choi
    20. Matthew J Watt
    21. Philipp Kaldis

    This article has been curated by 1 group:

    • Curated by eLife

      eLife Assessment

      The authors provide a useful integrated analytical approach to investigating MASLD focused on diverse multiomic integration methods. The strength of evidence for this new resource is solid, as analyses highlight the importance of previously-described pathophysiologic processes, as well as unveil several new mechanisms as key features of MASLD in obese patients.

    Reviewed by eLife, Review Commons