Review Commons

Latest preprint reviews

1. Transcriptional perturbation of LINE-1 elements reveals their cis -regulatory potential

   This article has 8 authors:

   1. Yuvia A Pérez-Rico
   2. Aurélie Bousard
   3. Lenka Henao Misikova
   4. Eskeatnaf Mulugeta
   5. Sérgio F de Almeida
   6. Alysson R Muotri
   7. Edith Heard
   8. Anne-Valerie Gendrel

   Reviewed by Review Commons

2. Cell size modulates ferroptosis susceptibility

   This article has 5 authors:

   1. Evgeny Zatulovskiy
   2. Magdalena B Murray
   3. Shuyuan Zhang
   4. Scott J Dixon
   5. Jan M Skotheim

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This important study highlights how cell size influences various cellular responses, with a particular focus on ferroptosis. The evidence presented is convincing, employing multiple model systems and experimental approaches to support the conclusions. This work will be of significant interest to the fields of cell size, ferroptosis, and cancer biology.

     [Editors' note: this paper was reviewed by Review Commons.]

   Reviewed by eLife, Review Commons

3. Quantitative comparison of PI(3,5)P ₂ biosensors reveals SnxA is the most sensitive and unbiased

   This article has 3 authors:

   1. Tiernan Swayhoover
   2. Claire C. Weckerly
   3. Gerald R. V. Hammond

   Reviewed by Review Commons

4. Metabolic Trans-Omic Analysis Reveals Key Regulatory Disruption of Energy Metabolism in Alzheimer’s Disease

   This article has 5 authors:

   1. Tomoharu Katayama
   2. Hikaru Sugimoto
   3. Keigo Morita
   4. Hirohisa Watanabe
   5. Shinya Kuroda

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This study presents a useful application of trans-omic network analyses to existing human brain datasets, generating systems-level insights into metabolic dysregulation in Alzheimer's disease. Overall, the authors' analytical choices are solid, with appropriate use of existing data and methods, and with many of their results confirming previous findings. However, some of the authors' key claims, related to previously unknown details of regulatory relationships, are only partially supported due to limitations in dataset cell-type resolution and network robustness, as well as a lack of functional validation. This work will be of interest to cellular or systems neurobiologists studying Alzheimer's disease and could serve as a helpful starting point for future work.

     [Editors' note: this paper was reviewed by Review Commons.]

   Reviewed by eLife, Review Commons

5. Mechanism of activation of an ancestral TEC kinase by PIP ₃

   This article has 9 authors:

   1. Eva Krötenheerdt
   2. Lucas Piëch
   3. Freia von Raußendorf
   4. Ronja Reinhardt
   5. Nicholas Wedige
   6. Hunter G. Nyvall
   7. Emma E. Walsh
   8. John E. Burke
   9. Thomas A. Leonard

   Reviewed by Review Commons

6. CD8 T lymphocytes redeploy embryonic cell cycle control mechanisms to facilitate rapid cell proliferation

   This article has 7 authors:

   1. D. A. Lewis
   2. A. Kar
   3. A. Savage
   4. V. Kelly
   5. D. Wright
   6. R. Zamoyska
   7. T. Ly

   Reviewed by Review Commons

7. Cross-species transcriptomic integration reveals a MIRO1-mediated macrophage–T cell axis in glioma

   This article has 11 authors:

   1. Zehui Du
   2. Menghan Li
   3. Brandon H Bergsneider
   4. Andy P Tsai
   5. Kwang Bog Cho
   6. Lily H Kim
   7. John Choi
   8. Gordon Li
   9. Tony Wyss-Coray
   10. Michael Lim
   11. Xinnan Wang

   Reviewed by Review Commons

8. MAVS is Important for Antiviral Defense Against Influenza A Virus in a Human Respiratory Epithelium Model

   This article has 7 authors:

   1. Maja Hemberg
   2. Anne Louise Hansen
   3. Jacob Storgaard
   4. Julia Blay-Cadanet
   5. Alice Pedersen
   6. Anne Laugaard Thielke
   7. Christian Kanstrup Holm

   Reviewed by Review Commons

9. Unconventional components complement the cryptic kinetochore of the ciliate Tetrahymena thermophila

   This article has 8 authors:

   1. Emine I. Ali
   2. Maximilian W. D. Raas
   3. Laura E. van Rooijen
   4. Paula Sobrevals Alcaraz
   5. Harmjan R. Vos
   6. Eelco C. Tromer
   7. Berend Snel
   8. Geert J.P.L. Kops

   Reviewed by Review Commons

10. An actomyosin-mediated mechanical mechanism for brain neural tube elevation

    This article has 4 authors:

    1. Juana De La O
    2. Chidera Okeke
    3. Gabriel L. Galea
    4. Adam C. Martin

    Reviewed by Review Commons