Latest preprint reviews

1. Evolution of novel sensory organs in fish with legs

   This article has 11 authors:

   1. Corey AH Allard
   2. Amy L Herbert
   3. Stephanie P Krueger
   4. Qiaoyi Liang
   5. Brittany L Walsh
   6. Andrew L Rhyne
   7. Allex N Gourlay
   8. Agnese Seminara
   9. Maude W Baldwin
   10. David M Kingsley
   11. Nicholas W Bellono

   Reviewed by Arcadia Science

2. Recording γ-secretase activity in living mouse brains

   This article has 9 authors:

   1. Steven S Hou
   2. Yuya Ikegawa
   3. Yeseo Kwon
   4. Natalia Wieckiewicz
   5. Mei CQ Houser
   6. Brianna Lundin
   7. Brian J Bacskai
   8. Oksana Berezovska
   9. Masato Maesako

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     Hou and colleagues describe the the use of a previously characterized FRET sensor for use in determining gamma secretase activity in the brain of living mice. In an approach that targeted the sensor to neurons, they observe patterns of fluorescent sensor readout suggesting clustered regions of secretase activity. These results once validated would be valuable in the field of Alzheimer's Disease research, yet further validation of the approach is required, as the current evidence provided is inadequate to support the conclusions.

   Reviewed by eLife, Arcadia Science

3. Staphylococcus aureus counters organic acid anion-mediated inhibition of peptidoglycan cross-linking through robust alanine racemase activity

   This article has 11 authors:

   1. Sasmita Panda
   2. Yahani P Jayasinghe
   3. Dhananjay D Shinde
   4. Emilio Bueno
   5. Amanda Stastny
   6. Blake P Bertrand
   7. Sujata S Chaudhari
   8. Tammy Kielian
   9. Felipe Cava
   10. Donald R Ronning
   11. Vinai C Thomas

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     In this useful study, the authors present convincing evidence linking the enzyme D-alanine-D-alanine ligase (Ddl), crucial for cell wall fortification, to organic acid exposure in Staphylococcus aureus. While it's established that organic acids impede bacterial growth, the researchers reveal a novel coping mechanism where S. aureus maintains elevated levels of D-alanine, the substrate for Ddl, to counteract this inhibition. This discovery illuminates a bacterial strategy for organic acid tolerance, offering new insights for microbiologists and potentially informing future antimicrobial approaches.

   Reviewed by eLife, Arcadia Science

4. Revealing global stoichiometry conservation architecture in cells from Raman spectral patterns

   This article has 6 authors:

   1. Ken-ichiro F. Kamei
   2. Koseki J. Kobayashi-Kirschvink
   3. Takashi Nozoe
   4. Hidenori Nakaoka
   5. Miki Umetani
   6. Yuichi Wakamoto

   Reviewed by Arcadia Science

5. Growing a cystic fibrosis-relevant polymicrobial biofilm to probe community phenotypes

   This article has 2 authors:

   1. Sarah Poirier
   2. Fabrice Jean-Pierre

   Reviewed by Arcadia Science

6. The LH receptor regulates hippocampal spatial memory and restores dendritic spine density in ovariectomized APP/PS1 AD mice

   This article has 6 authors:

   1. Megan Mey
   2. Sabina Bhatta
   3. Sneha Suresh
   4. Luis Montero Labrador
   5. Helen Piontkivska
   6. Gemma Casadesus

   Reviewed by Arcadia Science

7. High-volume, label-free imaging for quantifying single-cell dynamics in induced pluripotent stem cell colonies

   This article has 7 authors:

   1. Anthony J. Asmar
   2. Zackery A. Benson
   3. Adele P. Peskin
   4. Joe Chalfoun
   5. Mylene Simon
   6. Michael Halter
   7. Anne L. Plant

   Reviewed by Arcadia Science

8. Phylogenomics reveals coincident divergence between giant host sea anemones and the clownfish adaptive radiation

   This article has 16 authors:

   1. Aurelien De Jode
   2. Andrea M. Quattrini
   3. Tommaso Chiodo
   4. Marymegan Daly
   5. Catherine S. McFadden
   6. Michael L. Berumen
   7. Christopher P. Meyer
   8. Suzanne Mills
   9. Ricardo Beldade
   10. Aaron Bartholomew
   11. Anna Scott
   12. James D Reimer
   13. Kensuke Yanagi
   14. Takuma Fuji
   15. Estefanía Rodríguez
   16. Benjamin M. Titus

   Reviewed by Arcadia Science

9. Excessive F-Actin and Microtubule Formation Mediates Primary Cilia Shortening and Loss in Response to Increased Extracellular Osmotic Pressure

   This article has 5 authors:

   1. Hiroshi Otani
   2. Ryota Nakazato
   3. Faryal Ijaz
   4. Kanae Koike
   5. Koji Ikegami

   Reviewed by Arcadia Science

10. Pinpointing the microbiota of tardigrades: what is really there?

    This article has 6 authors:

    1. Bartłomiej Surmacz
    2. Daniel Stec
    3. Monika Prus-Frankowska
    4. Mateusz Buczek
    5. Łukasz Michalczyk
    6. Piotr Łukasik

    Reviewed by Arcadia Science