Respiratory Medicine

  1. Risk of COVID-19-related death among patients with chronic obstructive pulmonary disease or asthma prescribed inhaled corticosteroids: an observational cohort study using the OpenSAFELY platform

    1. Anna Schultze
    2. Alex J Walker
    3. Brian MacKenna
    4. Caroline E Morton
    5. Krishnan Bhaskaran
    6. Jeremy P Brown
    7. Christopher T Rentsch
    8. Elizabeth Williamson
    9. Henry Drysdale
    10. Richard Croker
    11. Seb Bacon
    12. William Hulme
    13. Chris Bates
    14. Helen J Curtis
    15. Amir Mehrkar
    16. David Evans
    17. Peter Inglesby
    18. Jonathan Cockburn
    19. Helen I McDonald
    20. Laurie Tomlinson
    21. Rohini Mathur
    22. Kevin Wing
    23. Angel Y S Wong
    24. Harriet Forbes
    25. John Parry
    26. Frank Hester
    27. Sam Harper
    28. Stephen J W Evans
    29. Jennifer Quint
    30. Liam Smeeth
    31. Ian J Douglas
    32. Ben Goldacre

    Reviewed by Rapid Reviews Infectious Diseases, ScreenIT

    5 evaluationsAppears in 2 listsLatest version Latest activity

  2. Autologous P63+ lung progenitor cell transplantation in idiopathic pulmonary fibrosis: a phase 1 clinical trial

    1. Shiyu Zhang
    2. Min Zhou
    3. Chi Shao
    4. Yu Zhao
    5. Mingzhe Liu
    6. Lei Ni
    7. Zhiyao Bao
    8. Qiurui Zhang
    9. Ting Zhang
    10. Qun Luo
    11. Jieming Qu
    12. Zuojun Xu
    13. Wei Zuo

    • Curated by eLife

      eLife Assessment

      This important study describes a first-in-human trial of autologous p63+ stem cells in patients with idiopathic pulmonary fibrosis, a lethal condition for which effective treatments are lacking. The authors provide convincing evidence that P63+ progenitor cell therapy can be safely delivered in patients with ILD, warranting movement to a Phase 2. However, given that this is a Phase 1 study with a small sample size, conclusions regarding efficacy should not yet be made.

    Reviewed by eLife

    7 evaluationsAppears in 1 listLatest version Latest activity

  3. Proteogenomic analysis of air-pollution-associated lung cancer reveals prevention and therapeutic opportunities

    1. Honglei Zhang
    2. Chao Liu
    3. Shuting Wang
    4. Qing Wang
    5. Xu Feng
    6. Huawei Jiang
    7. Li Xiao
    8. Chao Luo
    9. Lu Zhang
    10. Fei Hou
    11. Minjun Zhou
    12. Zhiyong Deng
    13. Heng Li
    14. Yong Zhang
    15. Xiaosan Su
    16. Gaofeng Li

    • Curated by eLife

      eLife Assessment

      This useful manuscript presents an interesting multi-modal omics analysis of lung adenocarcinoma patients with distinct clinical clusters, mutation hotspots, and potential risk factors identified in cases linked to air pollution. The findings show potential for clinical and therapeutic impact. Some of the conclusions remain incomplete as they are based on correlative or suggestive findings, and would benefit from further functional investigation and validating approaches.

    Reviewed by eLife

    8 evaluationsAppears in 1 listLatest version Latest activity

  4. Age Matters: COVID-19 Prevalence in a Vaping Adolescent Population – An Observational Study

    1. Nitin Tandan
    2. Manjari Rani Regmi
    3. Ruby Maini
    4. Abdisamad M. Ibrahim
    5. Cameron Koester
    6. Odalys Estefania Lara Garcia
    7. Priyanka Parajuli
    8. Mohammad Al-Akchar
    9. Mukul Bhattarai
    10. Abhishek Kulkarni
    11. Robert Robinson

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  5. Rapid detection of SARS-CoV-2 infection by multicapillary column coupled ion mobility spectrometry (MCC-IMS) of breath. A proof of concept study

    1. Claus Steppert
    2. Isabel Steppert
    3. William Sterlacci
    4. Thomas Bollinger

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  6. Bronchoscopy in Critically Ill COVID-19 Patients

    1. Pere Serra Mitjà
    2. Carmen Centeno
    3. Ignasi Garcia-Olivé
    4. Adrià Antuori
    5. Maria Casadellà
    6. Rachid Tazi
    7. Fernando Armestar
    8. Ester Fernández
    9. Felipe Andreo
    10. Antoni Rosell

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  7. Sputum ACE2, TMPRSS2 and FURIN gene expression in severe neutrophilic asthma

    1. U-BIOPRED Consortium
    2. Nazanin Zounemat Kermani
    3. Woo-Jung Song
    4. Yusef Badi
    5. Ali Versi
    6. Yike Guo
    7. Kai Sun
    8. Pank Bhavsar
    9. Peter Howarth
    10. Sven-Erik Dahlen
    11. Peter J. Sterk
    12. Ratko Djukanovic
    13. Ian M. Adcock
    14. Kian Fan Chung

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  8. Utility of the ROX Index in Predicting Intubation for Patients With COVID-19–Related Hypoxemic Respiratory Failure Receiving High-Flow Nasal Therapy: Retrospective Cohort Study

    1. Maulin Patel
    2. Junad Chowdhury
    3. Nicole Mills
    4. Robert Marron
    5. Andrew Gangemi
    6. Zachariah Dorey-Stein
    7. Ibraheem Yousef
    8. Matthew Zheng
    9. Lauren Tragesser
    10. Julie Giurintano
    11. Rohit Gupta
    12. Parth Rali
    13. Gilbert D'Alonzo
    14. Huaqing Zhao
    15. Nicole Patlakh
    16. Nathaniel Marchetti
    17. Gerard Criner
    18. Matthew Gordon

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  9. Findings and Prognostic Value of Lung Ultrasound in COVID ‐19 Pneumonia

    1. Jorge Castelao
    2. Desirée Graziani
    3. Joan B. Soriano
    4. José Luis Izquierdo

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  10. Evaluation on the diagnostic efficiency of different methods in detecting COVID-19

    1. Haitao Yang
    2. Yuzhu Lan
    3. Xiujuan Yao
    4. Sheng Lin
    5. Baosong Xie

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity
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