Molecular Biology

  1. Restriction of SARS-CoV-2 replication by targeting programmed −1 ribosomal frameshifting

    1. Yu Sun
    2. Laura Abriola
    3. Rachel O. Niederer
    4. Savannah F. Pedersen
    5. Mia M. Alfajaro
    6. Valter Silva Monteiro
    7. Craig B. Wilen
    8. Ya-Chi Ho
    9. Wendy V. Gilbert
    10. Yulia V. Surovtseva
    11. Brett D. Lindenbach
    12. Junjie U. Guo

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  2. The strength of a NES motif in the nucleocapsid protein of human coronaviruses is related to genus, but not to pathogenic capacity

    1. Maria Sendino
    2. Miren Josu Omaetxebarria
    3. Jose Antonio Rodriguez

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  3. The folate antagonist methotrexate diminishes replication of the coronavirus SARS-CoV-2 and enhances the antiviral efficacy of remdesivir in cell culture models

    1. Kim M. Stegmann
    2. Antje Dickmanns
    3. Sabrina Gerber
    4. Vella Nikolova
    5. Luisa Klemke
    6. Valentina Manzini
    7. Denise Schlösser
    8. Cathrin Bierwirth
    9. Julia Freund
    10. Maren Sitte
    11. Raimond Lugert
    12. Gabriela Salinas
    13. Toni Luise Meister
    14. Stephanie Pfaender
    15. Dirk Görlich
    16. Bernd Wollnik
    17. Uwe Groß
    18. Matthias Dobbelstein

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  4. Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA

    1. Shuai Yuan
    2. Lei Peng
    3. Jonathan J. Park
    4. Yingxia Hu
    5. Swapnil C. Devarkar
    6. Matthew B. Dong
    7. Qi Shen
    8. Shenping Wu
    9. Sidi Chen
    10. Ivan B. Lomakin
    11. Yong Xiong

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  5. Genes with 5′ terminal oligopyrimidine tracts preferentially escape global suppression of translation by the SARS-CoV-2 Nsp1 protein

    1. Shilpa Rao
    2. Ian Hoskins
    3. Tori Tonn
    4. P. Daniela Garcia
    5. Hakan Ozadam
    6. Elif Sarinay Cenik
    7. Can Cenik

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  6. Transmission of SARS-COV-2 from China to Europe and West Africa: a detailed phylogenetic analysis

    1. Wasco Wruck
    2. James Adjaye

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  7. Allosteric activation of SARS-CoV-2 RdRp by remdesivir triphosphate and other phosphorylated nucleotides

    1. Bing Wang
    2. Vladimir Svetlov
    3. Yuri I Wolf
    4. Eugene V Koonin
    5. Evgeny Nudler
    6. Irina Artsimovitch

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  8. Defective NET clearance contributes to sustained FXII activation in COVID-19-associated pulmonary thrombo-inflammation

    1. Hanna Englert
    2. Chandini Rangaswamy
    3. Carsten Deppermann
    4. Jan-Peter Sperhake
    5. Christoph Krisp
    6. Danny Schreier
    7. Emma Gordon
    8. Sandra Konrath
    9. Munif Haddad
    10. Giordano Pula
    11. Reiner K. Mailer
    12. Hartmut Schlüter
    13. Stefan Kluge
    14. Florian Langer
    15. Klaus Püschel
    16. Kosta Panousis
    17. Evi X. Stavrou
    18. Coen Maas
    19. Thomas Renné
    20. Maike Frye

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  9. Diversity of ACE2 and its interaction with SARS-CoV-2 receptor binding domain

    1. Jessie Low-Gan
    2. Ruiqi Huang
    3. Abigail Kelley
    4. Gabrielle Warner Jenkins
    5. Duncan McGregor
    6. Vaughn V. Smider

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  10. A Computational Approach to Evaluate the Combined Effect of SARS-CoV-2 RBD Mutations and ACE2 Receptor Genetic Variants on Infectivity: The COVID-19 Host-Pathogen Nexus

    1. Dana Ashoor
    2. Noureddine Ben Khalaf
    3. Maryam Marzouq
    4. Hamdi Jarjanazi
    5. Sadok Chlif
    6. M. Dahmani Fathallah

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